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Nicotine Dependence, Cigarettes clinical trials

View clinical trials related to Nicotine Dependence, Cigarettes.

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NCT ID: NCT03593239 Completed - Nicotine Dependence Clinical Trials

Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers

Start date: June 29, 2018
Phase: N/A
Study type: Interventional

A Ten Sequence, Open Label, Randomized Crossover Study Comparing Nicotine Pharmacokinetics of JUUL 1.7% and JUUL 5% Nicotine Salt Based ENDS Products, in Healthy Adult Smokers.

NCT ID: NCT03492463 Completed - Clinical trials for Nicotine Dependence, Cigarettes

The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products

ENDS-Switch
Start date: August 6, 2018
Phase: Phase 2
Study type: Interventional

This study plans to investigate whether using electronic cigarettes (e-cigarettes) or skin patches containing nicotine affects switching from smoking conventional combustible (burning) cigarettes.

NCT ID: NCT03473483 Withdrawn - Nicotine Dependence Clinical Trials

Cigarette Harm Reduction With Electronic Cigarette Use

NIDA-SREC
Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This is an observational, crossover study that will be examine use behaviors, chemical exposures, and biological effects of SREC compared to TC use in subjects confined to a research ward setting.

NCT ID: NCT03194958 Completed - Smoking Cessation Clinical Trials

Helping Poor Smokers Quit

Start date: June 5, 2017
Phase: N/A
Study type: Interventional

Using a 2x2 randomized factorial design, we will conduct a statewide field trial in Missouri to compare the relative and combined effects of these two strategies for augmenting an existing, evidence-based tobacco quitline program. Among 2000 low-income smokers, half will receive standard Missouri quitline services and half will receive new Specialized Quitline services targeted to this group. In each of these groups, half also will receive calls from a trained navigator to help them address unmet Basic Needs and the accompanying psychological distress that act as barriers to smoking cessation.

NCT ID: NCT03194919 Recruiting - Clinical trials for Nicotine Dependence, Cigarettes

Negotiating a Quit Date or Not in Online Interventions

Start date: September 12, 2017
Phase: N/A
Study type: Interventional

The primary purpose of the current study is to test the effect of providing users of automated web-based smoking cessation interventions with the option of negotiating and re-negotiating the quit date.

NCT ID: NCT03191825 Recruiting - Clinical trials for Nicotine Dependence, Cigarettes

Online Lapse Management Intervention

Start date: September 12, 2017
Phase: N/A
Study type: Interventional

The purpose of the trial is to test the adjunctive effect of adding a lapse management system to a best practices web- and mobile smoking cessation program.

NCT ID: NCT03011710 Completed - Clinical trials for Nicotine Dependence, Cigarettes

Epidemiology and Acute Oral Effects Electronic Cigarette

Start date: September 2015
Phase: N/A
Study type: Interventional

Electronic cigarettes are battery-powered vaporizers which have a similar feel to tobacco smoking. They do not produce cigarette smoke but rather an aerosol, which is frequently referred to as vapor. E-cigarettes are marketed as less harmful alternatives to smoking. Use and awareness of these devices has grown exponentially in recent years, with millions of people currently using them. The benefits and risks of electronic cigarette use are uncertain. There is no research on the acute oral effects of electronic cigarette in the scientific literature and no hungarian epidemiological survey has been performed in this topic. Regulation of electronic cigarettes varies across countries in the European Union, ranging from no regulation to banning them entirely. The investigators research could help to integrate the regulation of this device in Hungary and in the EU as well. The measurement of acute oral effects of e-cigarette and a hungarian epidemiological survey would be novel in this topic.

NCT ID: NCT02986711 Terminated - Clinical trials for Nicotine Dependence, Cigarettes

Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit

Start date: December 2013
Phase: N/A
Study type: Interventional

This study aims to pilot a method of collecting the post-discharge follow-up data required by the Joint Commission Tobacco Measure Set, using text messages sent to and received from patients' cellular-telephones. It also aims to assess whether specially designed relapse prevention text messages designed to encourage abstinence from smoking, can increase the proportion of smokers who remain abstinent during the first month after discharge from hospital.

NCT ID: NCT02723162 Completed - Clinical trials for Nicotine Dependence, Cigarettes

Translational Neuropsychopharmacology Research of Nicotine Addiction

Start date: May 4, 2016
Phase: Phase 2
Study type: Interventional

This study will examine the effects of combining Varenicline (VRN) and N-acetylcysteine (NAC) on neural circuitry function and treating nicotine addiction. Healthy adult nicotine dependent cigarette smokers interested in quitting (n=110) will be randomized to one of four PBO-controlled conditions for 4 weeks: 1) VRN+NAC, 2) VRN+PBO, 3) NAC+PBO or 4) PBO+PBO. Following 1 week of medication, participants will be contingently reinforced for 3 days of smoking abstinence and be scanned using functional magnetic resonance imaging (fMRI) techniques, while nicotine deprived during a resting state and a cue-reactivity (CR) task. Participants will be followed over the next 3 weeks of treatment and clinical variables will be assessed.

NCT ID: NCT02367391 Completed - Clinical trials for Nicotine Dependence, Cigarettes

Penn State TXT2Quit Study

Start date: January 2015
Phase: N/A
Study type: Interventional

This study is evaluating the feasibility and short term smoking cessation outcomes of an automated smoking cessation intervention delivered via mobile phone text messaging as an adjunct to Varenicline in a primary care setting.