Newly-diagnosed Glioblastoma Clinical Trial
Official title:
Angiotensin II Receptor Blockers, Steroids and Radiotherapy in Glioblastoma- A Randomized Multicenter Trial
To assess the efficacy of an Angiotensin-II inhibitor (Losartan) to reduce peritumoral edema in newly diagnosed glioblastoma patients.
Multicentre, randomized (1:1), double blinded trial:- Arm A: Standard of care (Radiotherapy with concomitant temozolomide followed by monthly cures of temozolomide ) + Losartan 50mg*2/day until the halting for any reason - Arm B: Standard of care (Radiotherapy with concomitant temozolomide followed by monthly cures of temozolomide + Placebo 2/day until the halting for any reason. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05447195 -
Phase 2 Study of CAN008 in Subjects With GBM
|
Phase 2 |