Bed-side Ultrasound in Neutropenic Enterocolitis

Neutropenic Enterocolitis Clinical Trial

Official title: Bed-side Ultrasound in the Evaluation of Gastro-intestinal Tract and Neutropenic Enterocolitis (NEC) in Neutropenic Patients.

Status Completed

Clinical Trial Summary

Neutropenic enterocolitis (NEC) is a life-threatening complication of leukemic and solid tumors patients (pts) treated with chemotherapy (CHT) with high mortality rate up to 50-100%. Perforation occurs in 5%-10% of cases. Early diagnosis is crucial to start conservative medical management (CMM), which appears the optimal strategy for most cases. NEC should be always suspected in Neutropenic pts with abdominal pain, fever and diarrhea. Ultrasound (US) can be used to evaluate bowel-wall thickening (BWT). The objective of this study is to evaluate prospectively if US can detect early signs of NEC and guide a prompt treatment (CMM or surgical) and thus reduce mortality.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Enterocolitis
• Neutropenic Enterocolitis

• NCT number: NCT04813679
• Study type: Observational
• Source: Azienda Ospedaliero, Universitaria Pisana
• Status: Completed
• Start date: March 2007
• Completion date: January 2018