Bed-side Ultrasound in Neutropenic Enterocolitis

Neutropenic Enterocolitis Clinical Trial

Official title:
Bed-side Ultrasound in the Evaluation of Gastro-intestinal Tract and Neutropenic Enterocolitis (NEC) in Neutropenic Patients.

Status Completed

Clinical Trial Summary

Neutropenic enterocolitis (NEC) is a life-threatening complication of leukemic and solid tumors patients (pts) treated with chemotherapy (CHT) with high mortality rate up to 50-100%. Perforation occurs in 5%-10% of cases. Early diagnosis is crucial to start conservative medical management (CMM), which appears the optimal strategy for most cases. NEC should be always suspected in Neutropenic pts with abdominal pain, fever and diarrhea. Ultrasound (US) can be used to evaluate bowel-wall thickening (BWT). The objective of this study is to evaluate prospectively if US can detect early signs of NEC and guide a prompt treatment (CMM or surgical) and thus reduce mortality.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04813679
Study type	Observational
Source	Azienda Ospedaliero, Universitaria Pisana
Contact
Status	Completed
Phase
Start date	March 2007
Completion date	January 2018

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See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT02145923` - Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis	Phase 1/Phase 2
Recruiting	`NCT04438278` - Profile Fecal Analysis of Neutropenic Enterocolitis
Recruiting	`NCT01699516` - Non-invasive Contrast Enhanced Ultrasound Sonography in Intestinal Acute Graft-vs-Host Disease	N/A