Neutropenia Clinical Trial
Official title:
Obtaining Early Diagnosis and Prognosis in Urgent Sepsis (OEDIPUS) Study
Objectives: Invasive infections are the leading cause of morbidity and mortality in patients
treated for hematological malignancies. Blood cultures are often negative in neutropenic
patients because of low-burden of organisms, previous antibiotic therapy or non-infectious
reason of fever. More rapid, accurate and sensitive diagnostic tools are needed.
Hypothesis: Multiplex real-time PCR may detect microbial DNA in neutropenic patients before
febrile episode. To investigate this hypothesis, EDTA-blood was routinely collected for
multiplex PCR at admission and 3x/week thereafter until discharge or recovery from
neutropenia
n/a
Observational Model: Cohort, Time Perspective: Prospective
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