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Clinical Trial Summary

To determine the efficacy and safety of nerve growth factor in the treatment of limbal stem cell deficiency (LSCD) associated with neurotrophic cornea.

Clinical Trial Description

This is a prospective open-label pilot study evaluating the role of cenegermin-bkbj for the treatment of LSCD with associated neurotrophic keratopathy. Patient diagnosed with LSCD with neurotrophic cornea who have failed conventional treatment such as artificial tears are enrolled in the study after a 2 week washout period. Patient are then treated with cenegermin-bkbj over an 8 week period. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT04552730
Study type Observational
Source Stanford University
Status Completed
Start date October 14, 2020
Completion date May 4, 2021

See also
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