Neuroimage Genome Study of Neuroplasticity Associated With Microgravity

Status Active, not recruiting

Clinical Trial Summary

This clinical trial investigates the neuroplasticity and cognitive status changes of the human brain in microgravity. To explore the relationship between cognitive status changes and brain functional activities, gray matter and white matter changes under microgravity exposure, screen and identify representative image markers, so as to provide decision-making information for the cognitive status changes of relevant personnel under microgravity environment.

Clinical Trial Description

MRI has the advantage of non-invasive and non-radiation, and imaging the human brain after exposure to microgravity can reveal the neuroplastic changes in the astronaut's brain and discover the characteristics of functional activities behind it. The purpose of this study is to explore the image features and cognitive state related information related to the changes of human brain neuroplasticity under microgravity environment, and to identify the related image markers. At the same time, the pathophysiological mechanism is preliminarily discussed in this study. This study is helpful for us to explore the sensitivity of different brain structures and brain functions to space microgravity environment, so as to further understand the role and influence of space missions on brain health. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06350422
Study type	Observational
Source	Chinese PLA General Hospital
Contact
Status	Active, not recruiting
Phase
Start date	January 1, 2022
Completion date	December 31, 2024

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