Neuropathy, Optic Clinical Trial
Official title:
Study of Peripapillary Vasculature With OCT-angiography in Arteritic and Non Arteritic Anterior Ischemic Neuropathy After Oedema Disappearance
Anterior ischaemic optic neuropathy results from infarction of retrolaminar portion of the
optic nerve head, caused by occlusion of the posterior ciliary artery. Non arteritic anterior
ischaemic optic neuropathy affects more frequently people between 50 and 70 years of age,
with vasculopathic risk factors. Arteritic anterior ischaemic optic neuropathy is caused by
the Horton disease, affects an older population and is an ophthalmologic emergency because of
the bilateralisation's risk.
The aim of this study is to compare the peripapillar vascular density of anterior ischaemic
optic neuropathy eyes (arteritic and non arteritic) with normal eyes after the disappearance
of the papillar edema, with oCT-angiography.
The investigators will include patients with anterior ischaemic optic neuropathy and normal
patients. For each participant, the investigators will estimate the best visual acuity,
intra-ocular pressure, make a fondus, measurement of retinal nervous layer thickness,
ganglionar cells layer thickness, and a macular and papillar OCT angiography during a
consultation (duration 30 min).
The investigators will be able to know if
- there is a modification of the peripapillary vascularisation subsequent to the occlusion
of the posterior ciliary artery
- there is a difference between arteritic and non arteritic anterior ischaemic optic
neuropathy,
- there is a repercussion of the neuropathy on the retinal layers,
- there is a difference in peripapillar vascularisation by age.
Anterior ischaemic optic neuropathy results from infarction of retrolaminar portion of the
optic nerve head, caused by occlusion of the posterior ciliary artery. Non arteritic anterior
ischaemic optic neuropathy affects more frequently people between 50 and 70 years of age,
with vasculopathic risk factors. Arteritic anterior ischaemic optic neuropathy is caused by
the Horton disease, affects an older population and is an ophthalmologic emergency because of
the bilateralisation's risk.
The aim of this study is to compare the peripapillar vascular density of anterior ischaemic
optic neuropathy eyes (arteritic and non arteritic) with normal eyes after the disappearance
of the papillar edema, with oCT-angiography.
The investigators will include patients with anterior ischaemic optic neuropathy and normal
patients. For each participant, the investigators will estimate the best visual acuity,
intra-ocular pressure, make a fondus, measurement of retinal nervous layer thickness,
ganglionar cells layer thickness, and a macular and papillar OCT angiography during a
consultation (duration 30 min).
The investigators will be able to know if
- there is a modification of the peripapillary vascularisation subsequent to the occlusion
of the posterior ciliary artery
- there is a difference between arteritic and non arteritic anterior ischaemic optic
neuropathy,
- there is a repercussion of the neuropathy on the retinal layers,
- there is a difference in peripapillar vascularisation by age.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05931250 -
Alternating and Direct Current Stimulation for Neuropathic Eye Pain
|
N/A |