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Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses — A1AT for NMO  

Neuromyelitis Optica Clinical Trial

Official title:
A Single Center Open Label Pilot Study of Alpha1-Antitrypsin: A Novel Treatment to Mitigate Neuromyelitis Optica Attacks

Clinical Trial Summary

Neuromyelitis Optica (NMO) is a rare, devastating demyelinating disease of the central nervous system (CNS) that has different causes and treatments from the more common demyelinating disease multiple sclerosis (MS). Current NMO therapies are nonspecific and have varying and often suboptimal benefit. The investigators will evaluate whether use of alpha1-antitrypsin (A1AT, an FDA-approved medication for patients with congenital deficiency of A1AT associated with emphysema) can benefit acute attacks of NMO, improving patient disability and quality of life.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02087813
Study type Interventional
Source Stanford University
Contact
Status Withdrawn
Phase Phase 1
Start date March 2014
View Details
See also
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