Rocuronium Consumption in Etomidate-based and Propofol-based General Anesthesia Under Sevoflurane

Neuromuscular Monitoring Clinical Trial

Official title: Consumption of Rocuronium Under Etomidate-based Versus Propofol-based Maintenance of General Anesthesia Under Different Concentration of Sevoflurane- BIS Guided Clinical Trial in a Closed Loop Infusion System

Status Completed

Clinical Trial Summary

Different concentration of sevoflurane was given to maintain anesthesia. The dose of propofol to maintain BIS between 40-60 and the consumption of rocuronium was recorded and evaluated.

Clinical Trial Description

2 age group of patients was selected, 40-60 years and above 60 years. Maintenance of anesthesia was carried out using different concentration of Sevoflurane, ie MAC 0.5, 0.75 and 1.0. Bis value was kept between 40-60 and the dose of propofol required was recorded. Rocuronium infusion given in a close loop infusion system for different group was tabulated. The results was then analysed. ;

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Neuromuscular Monitoring

• NCT number: NCT02711917
• Study type: Interventional
• Source: Tianjin Medical University General Hospital
• Status: Completed
• Phase: N/A
• Start date: July 2015
• Completion date: January 2016