Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques

Neuromodulation Clinical Trial

— OMNIBUS2023  

Official title:

Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06251479
• Other study ID #: OMNIBUS2023
• Status: Recruiting
• Phase: N/A
• Start date: August 16, 2023
• Est. completion date: August 16, 2026

Study information

• Verified date: January 2024
• Source: IRCCS Centro Neurolesi "Bonino-Pulejo"
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive and analyze our own and others' actions. This is essential to fully understand the complexity of our social behaviors. The knowledge of these mechanisms has a high value and relevant implications for many research fields both within and outside the neurosciences. The project aims to study the neurobehavioral correlates of verbal and non-verbal communication. Through the use of non-invasive behavioral and neurophysiological techniques, the study intends to highlight the neurobehavioral markers that allow to quantify the temporal evolution of communication dynamics in healthy subjects.

Description:

Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive and analyze our own and others' actions. This is essential to fully understand the complexity of our social behaviors. The knowledge of these mechanisms has a high value and relevant implications for many research fields both within and outside the neurosciences. The project aims to study the neurobehavioral correlates of verbal and non-verbal communication. Through the use of non-invasive behavioral and neurophysiological techniques, the study intends to highlight the neurobehavioral markers that allow to quantify the temporal evolution of communication dynamics in healthy subjects.

1. the investigators intend to verify whether individual differences in the ability to discriminate the verbal and non-verbal signals of others are reflected in significant differences in the way the same actions are performed.

2. the investigators intend to quantify the behavioral variables during the execution of the action and observe how these are modified in the passage from a single execution to an interaction context.

3. the investigators intend to study how the interactive context influences the cerebral and cortico-muscular oscillatory dynamics during the preparation of the action.

4. the investigators intend to verify whether the activity of the motor system contributes not only to the execution of the action but also, if and, if so, to the perception of the actions of others

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: August 16, 2026
• Est. primary completion date: December 28, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:

• Age range between 18 and 55 years

• written informed consent

• healthy subjects

Exclusion Criteria:

• epilepsy or at risk of epileptic seizures,

• cardiac pacemaker wearers,

• presence of an implanted infusion pump,

• metal plaques in the skull or metal objects in the eye and skull taking neuroleptic drugs or tricyclic antidepressants,

• migraine or at risk of developing this disease.

Related Conditions & MeSH terms

• Neuromodulation
• Neuroscience

Intervention

Behavioral:
• behavioral 1
verbal and non verbal tasks
• behavioral 2
verbal and non verbal tasks with other partecipants

Device:
• neuromodulation 1
registration with neurophysiological tecniques during verbal and non verbal tasks
• neuromodulation 2
registration with neurophysiological tecniques during verbal and non verbal tasks with other partecipants

Locations

Country	Name	City	State
Italy	IRCCS Centro Neurolesi Bonino Pulejo	Messina

Sponsors (1)

Lead Sponsor	Collaborator
IRCCS Centro Neurolesi "Bonino-Pulejo"

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Embodiment Scale	patients have to experience rubber hand illusion first with a silicon and and second with a robotic hand. the embodiment variance is evaluted in the two condition with the embofiment scale	1 hour
Secondary	Embodiment Scale	patients have to experience with a single-pulse Transcranial magnetic stimulation during seeing a visual cue where a human hand is stung. the questionnaire evalute the embodiment variance	1 hour