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Neuroma clinical trials

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NCT ID: NCT05411224 Recruiting - Morton Neuroma Clinical Trials

Investigation of the Effect of Custom Made Insoles on Foot Pressure Distribution and Gait Parameters in Patients With Morton's Neuroma

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The aim of our study is to investigate the effect of the use of custom made insoles in the treatment of Morton's neuroma on foot pressure, temporal and spatial gait parameters.

NCT ID: NCT05344261 Withdrawn - Amputation Clinical Trials

Effect of Prophylactic TMR and RPNI on Neuroma and Phantom Limb Pain

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to analyze the efficacy of novel interventions in post-amputation surgical care (specifically Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interface) on post-amputation pain and functional outcomes at the time of amputation. These novel interventions have been shown to be successful in treating the downstream effects of amputations (pain, phantom limb pain, neuroma pain, etc.), but has not been studied in a randomized manner at the time of amputation.

NCT ID: NCT05244369 Completed - Neuroma Amputation Clinical Trials

Efficacy of Acupuncture in Patients With Lower Extremity Amputation With Neuroma

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Neuroma often occurs after major nerve damage or transection and can be diagnosed with pain at the tip of the stump, positive tinel, imaging (USG/MR). Various treatment methods are used for neuropathic pain, including pharmacological agents, intralesional steroid and local anesthetic injection, alcohol, phenol, radiofrequency or cryotherapy, ablation and surgical applications. Exercise (ROM and relaxation), TENS, biofeedback, hypnosis, acupuncture, psychotherapy, mirror therapy can be used in the treatment of neuropathic pain in amputees. In this study, the investigators aimed to examine the effectiveness of acupuncture on pain, neuroma size and functional status in individuals with lower extremity amputation with neuroma.

NCT ID: NCT05012488 Completed - Pes Planus Clinical Trials

Comparison of the Effects of Morton's Neuroma on Foot Pressure Distribution and Gait Parameters in Pes Planus and Pes Cavus Patients

Start date: July 1, 2021
Phase:
Study type: Observational

The aim of our study is to compare the effect of Morton's neuroma in feet with pes planus and pes cavus on foot pressure and temporal and spatial gait parameters.

NCT ID: NCT05009394 Recruiting - Phantom Limb Pain Clinical Trials

Surgical Treatments for Postamputation Pain

Start date: June 20, 2023
Phase: N/A
Study type: Interventional

This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP). The three surgical treatments are Targeted Muscles Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), and an active control (neuroma excision and muscle burying). Patients will be follow-up for 4 years.

NCT ID: NCT05008185 Recruiting - Neuroma Clinical Trials

Regenerative Peripheral Nerve Interfaces to Treat Painful Digit and Hand Neuromas After Amputation

Start date: October 5, 2021
Phase:
Study type: Observational

This study is being done to demonstrate the effectiveness of Regenerative Peripheral Nerve Interfaces (RPNI) surgery in treating symptomatic neuromas of the hand and digits following amputation compared to standard of care using a Prospective, Observational Trial

NCT ID: NCT04931056 Completed - Tumor Clinical Trials

A Post Market Clinical Follow-up Study on Biomet Microfixation HTR PEKK (Midface), Facial & Mandibular Plates.

Start date: October 1, 2021
Phase:
Study type: Observational

This study will address medical devices manufactured by Biomet Microfixation (d.b.a. Zimmer Biomet) designed for fixation and stabilization of the facial and mandibular skeleton.

NCT ID: NCT04865679 Recruiting - Amputation Clinical Trials

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

REPOSE-XL?
Start date: March 2, 2022
Phase: N/A
Study type: Interventional

This pilot study evaluates the tolerability and feasibility of the Axoguard Large-Diameter Nerve Cap (sizes 5-7 mm) for protecting and preserving terminated nerve endings after limb trauma or amputation when immediate attention to the nerve injuries is not possible.

NCT ID: NCT04845451 Completed - Cluster Headache Clinical Trials

The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache

Start date: June 9, 2021
Phase:
Study type: Observational

Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated .

NCT ID: NCT04538417 Completed - Phantom Limb Pain Clinical Trials

C-RFA of Residual Limb Neuroma

Start date: October 27, 2019
Phase: N/A
Study type: Interventional

To assess changes in pain, physical function, and health-related quality of life in patients with post-amputation neuroma-associated residual limb pain after cooled radiofrequency ablation.