Dysphagia & Deep Cervical Flexor Muscles

Status Completed

Clinical Trial Summary

Cervical posture is vital for normal swallowing function. Changes in cervical posture during swallowing alter the bolus flow and swallowing kinematics through changes in gravity and oropharyngeal space. The hyoid bone does not articulate with any bone, so it requires adequate tension of the hyolaryngeal complex and proper cervical postural alignment to maintain its stabilization and position. Changes in cervical posture and stabilization can cause changes in hyoid bone position and kinematics through muscles and ligaments which may lead to decrease in hyoid elevation, loss of optimal strength of the suprahyoid and infrahyoid muscles due to disrupted length-tension relationship, and an increased risk of aspiration due to insufficient laryngeal elevation. Further, deterioration in cervical posture and decreased stabilization resulting from cervical muscle weakness or/both endurance could affect the control and strength of masticatory muscles, tongue muscles and suprahyoid - infrahyoid muscles, which are involved in swallowing function. Whereby DCF weakness gives rise to inadequate cervical stabilization, change in hyoid bone stabilization, alterations in suprahyoid and infrahyoid muscle function, and decreased laryngeal elevation may adversely affect the normal function of the swallowing related muscles. Thus, decreased cervical stabilization, which is often seen in neurological diseases, may be related to neurogenic dysphagia. Given the known changes in cervical stabilization as a consequence of neurologic injury, the additional impact on swallowing or a potentially already neurologically-disordered swallow is considered. Thus, loss of cervical stabilization may be one of the factors affecting dysphagia in patients with neurological diseases providing more information on all potential factors contributing to swallow impairment, potentially leading to more targeted and effective swallowing interventions. However, there is no study investigating the role of the DCF muscles in dysphagia. Therefore, the aim of the present study was to comparison of deep cervical flexor muscle strength and endurance in patients with and without neurogenic dysphagia.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06278025
Study type	Observational [Patient Registry]
Source	Atilim University
Contact
Status	Completed
Phase
Start date	September 1, 2019
Completion date	February 1, 2024

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT03711474` - Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)	Phase 4
Enrolling by invitation	`NCT04074356` - Non-invasive Markers of Esophageal Function in Adults	N/A
Suspended	`NCT04349462` - Post Critical Illness Dysphagia in the Intensive Care Unit	N/A
Not yet recruiting	`NCT05982977` - Study on the Effect Mechanism of Acupuncture Combined With Swallowing Training in Oral Dysphagia of Stroke	N/A
Recruiting	`NCT03605381` - MORbidity PRevalence Estimate In StrokE
Active, not recruiting	`NCT03455608` - PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer	N/A
Active, not recruiting	`NCT03604822` - Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS	N/A
Recruiting	`NCT03682081` - Interventions for Patients With Alzheimer's Disease and Dysphagia	N/A
Completed	`NCT05700838` - Refining Cough Skill Training in Parkinson's Disease and Dysphagia	Phase 1
Not yet recruiting	`NCT04064333` - Slow-Stream Expiratory Muscle Strength Training for Veterans With Dysphagia Living in Long-term Care	N/A
Not yet recruiting	`NCT02724761` - Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion	N/A
Completed	`NCT02927691` - Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial	Phase 2
Completed	`NCT01919112` - Fostering Eating After Stroke With Transcranial Direct Current Stimulation	N/A
Completed	`NCT01370083` - Tongue Pressure Profile Training for Dysphagia Post Stroke	Phase 2
Withdrawn	`NCT01200147` - Effectiveness of Rupture of Schatzki's Ring Using Biopsy Forceps Versus SIngle Dilation	N/A
Completed	`NCT01723358` - Neuromuscular Electrical Stimulation (NMES) Treatment Technique Therapy in the Management of Young Infants With Severe Dysphagia	Phase 2
Completed	`NCT00570557` - Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia	N/A
Recruiting	`NCT00166751` - Sonographic Assessment of Laryngeal Elevation	N/A
Completed	`NCT00717028` - Functional Endoscopic Evaluation of Swallowing	N/A
Completed	`NCT01476241` - Percutaneous Endoscopic Gastrostomy Tube Placement by Otorhinolaryngologist	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Dysphagia and Deep Cervical Flexor Muscles

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms