An Appraisal of Minimal Invasive Surgery for Thoracic Neurogenic Tumour

Neurogenic Thoracic Tumors Clinical Trial

— DIUOP  

Official title:

An Appraisal of Minimal Invasive Surgery for Thoracic Child Neurogenic Tumour. A Multicentric Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04554173
• Other study ID #: 20-HPNCL-01
• Status: Completed
• Start date: April 24, 2020
• Est. completion date: December 30, 2021

Study information

• Verified date: August 2021
• Source: Fondation Lenval
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Mediastinal neurogenic tumors are relatively rare in children. Surgical resection is essential. Minimal invasive surgery is more and more used in pediatric population, but his evaluation for resection of thoracic neurogenic tumors is little studied. Thoracotomy has specific long terms post operative complications. When compared to thoracotomy, thoracoscopy shows less operative blood loss, shorter duration of chest tube ans length of stay. Recently, the indications of thoracoscopic approach have been assessed according to the presence or absence of image-defined risk factors (IDRF) at diagnosis and after preoperative chemotherapy in a monocentric retrospective study. The investigators aimed to conduct a multicentric retrospective study to assess the role of thoracoscopy in neurogenic thoracic tumours according to the presence or absence of IDRF at diagnosis, the surgical complications and outcome.

Description:

Mediastinal neurogenic tumors are relatively rare in children. Surgical resection is usually essential in there treatment. Minimal invasive surgery with video assisted thoracic surgery is more and more used in pediatric population, but his evaluation for resection of thoracic neurogenic tumors is little studied. Thoracotomy has specific long terms post operative complications including scoliosis, shoulder elevation, winged scapula and asymmetric nipples. When compared to thoracotomy, thoracoscopy shows less operative blood loss, shorter duration of chest tube and length of stay. Recently, the indications of thoracoscopic approach have been assessed according to the presence or absence of image-defined risk factors (IDRF) at diagnosis and after preoperative chemotherapy in a monocentric retrospective study. The authors concluded that thoracoscopy could be used for all paravertebral locations without IDRF except the IDRF of T9-T12 location and the presence of an intraspinal component but should be avoided for perivascular locations due to tight adherences of the tumour to the vessels and hence the risk of important bleeding. The investigators aimed to conduct a multicentric retrospective study to assess the role of thoracoscopy in neurogenic thoracic tumours according to the presence or absence of IDRF at diagnosis, the surgical complications and outcome.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: December 30, 2021
• Est. primary completion date: October 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 17 Years

Eligibility

Inclusion Criteria:

All children operated for neurogenic thoracic tumors with minimal invasive surgery Exclusion Criteria: -

Related Conditions & MeSH terms

• Neurogenic Thoracic Tumors
• Thoracic Neoplasms

Intervention

Procedure:
• surgical resection neurogenic tumors
Patient who was treated for a thoracic neurogenic tumor by minimally invasive surgery

Locations

Country	Name	City	State
France	Hôpitaux Pédiatrique de Nice CHU Lenval	Nice

Sponsors (1)

Lead Sponsor	Collaborator
Fondation Lenval

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Reason of failure of thoracoscopy	counting of number of bleeding and surgical difficulties for a period of 30 days after surgery	at inclusion
Secondary	Post operative complications	duration of hospitalization	at inclusion
Secondary	Post operative complications number 2	Duration of chest tube	at inclusion