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Selumetinib Paediatric NF1 Japan Study

Neurofibromatosis Type 1 Clinical Trial

Official title:
A Phase 1 Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Selumetinib, a Selective Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor, in Japanese Paediatric Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable and Symptomatic Plexiform Neurofibromas (PN)

Clinical Trial Summary

This is a phase I open label study designed to evaluate the safety, tolerability, PK and efficacy of selumetinib in Japanese paediatric patients with neurofibromatosis type 1 and inoperable and symptomatic plexiform neurofibroma.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04495127
Study type Interventional
Source AstraZeneca
Contact
Status Completed
Phase Phase 1
Start date August 31, 2020
Completion date March 24, 2023
View Details
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