Clinical Trials Logo
  1. Home
  2. Neurofibroma
  3. NCT05891847

Non-interventional Study of Patients With PN NF1 Starting Selumetinib in Russia

Neurofibroma Clinical Trial

Official title:
Non-interventional Study of Patients With Plexiform Neurofibromas and Neurofibromatosis Type I Starting Selumetinib in Russia

Clinical Trial Summary

The purpose of this study is to evaluate the effectiveness, safety of selumetinib and patient's parameters of symptomatic inoperable PN NF1 in real clinical practice in Russia

Clinical Trial Description

This study will be non-interventional retrospective and prospective study. Assessment of parameters will be carried out as if a patient is treated in real-life clinical setting. The patients should be enrolled into this project after evaluation of eligibility criteria by an investigator 10 clinical sites. No additional procedures besides those already used in the routine clinical practice will be applied to the patients. Study population will consist of pediatric patients aged 3 years and older with NF1 and symptomatic inoperable PN who were prescribed with selumetinib ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05891847
Study type Observational
Source AstraZeneca
Contact AstraZeneca Clinical Study Information Center
Phone 1-877-240-9479
Email information.center@astrazeneca.com
Status Recruiting
Phase
Start date March 21, 2023
Completion date March 20, 2026
View Details
See also
  Status Clinical Trial Phase
Completed NCT01347307 - Stereotactic Body Radiotherapy for Spine Tumors N/A
Recruiting NCT06322342 - Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent Phase 2
Completed NCT00314119 - Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1
Withdrawn NCT01567787 - Proton Radiation Therapy for Spinal Tumors N/A
Terminated NCT00716469 - Phase I Clinical Study of the Safety of Photodynamic Therapy (PDT) Using LS11 in Children With Plexiform Neurofibromas Phase 1
Active, not recruiting NCT03820778 - Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1 N/A
Active, not recruiting NCT00924196 - Natural History Study of Patients With Neurofibromatosis Type I
Recruiting NCT05199376 - Evaluation of Percutaneous Cryotherapy in the Treatment of Plexiform Neurofibromas and Unresectable Neurofibromas in Neurofibromatosis Type 1 N/A
Completed NCT01031901 - Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1) Phase 1