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Clinical Trial Summary

Alzheimer's disease, Parkinson's disease, and Huntington's disease are common neurodegenerative diseases. Tau is a microtubule-associated protein, and aggregated tau resulting from hyperphosphorylation is a pathological feature of a group of neurodegenerative diseases known as tauopathies. The 18F-T807 (AV1451) molecular probe is a novel molecularly targeted imaging agent that exhibits high affinity and good selectivity for tau.


Clinical Trial Description

In this study, 18F-T807 (AV1451) molecular probe PET/CT was used to monitor the regional distribution and the degree of deposition in patients with neurodegenerative diseases, and compared with clinical symptoms to evaluate its value in the early differential diagnosis of neurodegenerative diseases. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04926259
Study type Interventional
Source First Affiliated Hospital of Fujian Medical University
Contact Shaobo Yao, PhD
Phone 86-0591-87981618
Email yaoshaobo008@163.com
Status Recruiting
Phase Early Phase 1
Start date November 1, 2021
Completion date December 1, 2024

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