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Clinical Trial Summary

In terms of the diagnostic technology of brain neurodegenerative diseases, the injection of positron tracers into the human body, so that it can combine with the corresponding protein, and show its distribution through PET imaging is a mature technology in the industry. At present, several research groups around the world are working on the development and clinical efficacy evaluation of their respective tau imaging agent compounds.This clinical research project intends to display the abnormal changes of tau protein in living brain through [18F]PM-PBB3 PET imaging, which is a second-generation tracer further optimized on the basis of [11C]PBB3, and has the advantages of closer binding to tau protein entanglement and less non-specific binding than similar imaging agents. Better image quality and a wider range of clinical applications.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT06344845
Study type Interventional
Source Peking Union Medical College Hospital
Contact Chenhao Jia, M.D.
Phone 86+18548703382
Email jiachenhao24@163.com
Status Recruiting
Phase N/A
Start date November 1, 2022
Completion date November 2025

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