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Retinal Neurodegenerative and Vascular Changes in Diabetic Patients

Diabetic Retinopathy Clinical Trial

Official title:
Retinal Neurodegenerative and Vascular Changes in Diabetic Patients: an OCT-based Comparative Study

Clinical Trial Summary

Using Optical Coherence Tomography and ImageJ software the investigators will analyze retinal and choroidal vascular changes and their impact on retinal layers among patients with diabetes without retinopathy and patients with diabetes and retinopathy.

Clinical Trial Description

Relieving the burden of diabetic retinopathy treatment require a prompt and non-invasive assessment of diabetic patients before the occurence of diabetic retinopathy. Since OCT is capable of imaging retina with such a high precision, retinal changes occuring before any clinical signs of retinopathy, such as microaneurysm or haemorrhages, can now be assessed. In the present study the investigators are analyzing the connection between retinal arteries and veins regarding lumen diameter, vessel wall thickness and their correlation with retinal nerve fiber layer and ganglion cell layer thickness. Moreover, using binarization of the choroid the investigators will assess its relationship with outer retina layers, such as retinal pigment epithelium and photoreceptors. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04637217
Study type Observational
Source Iuliu Hatieganu University of Medicine and Pharmacy
Contact
Status Completed
Phase
Start date July 1, 2018
Completion date July 1, 2019
View Details
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