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CBF and NCF Changes With Brain Radiation

Brain Metastases Clinical Trial

Official title:
Use of Novel MRI Techniques Before and After Brain Radiotherapy With Parallel Assessments of Neurocognitive Function

Clinical Trial Summary

This study will be a dual-arm prospective longitudinal cohort study for patients with brain metastases, at least one of which is appropriate for radiotherapy, to explore brain and cognitive changes following SRS or WBRT and evaluate the feasibility of a novel MRI protocol to identify potential radiological biomarkers of NCF decline. Patients diagnosed with brain mets will be assigned to either Arm A or Arm B, depending on their treatment plan. Patients in Arm A will be treated with SRS. Patients in Arm B will be treated with WBRT. Patients' neurocognitive function will be assessed before their radiation treatment and followed up for 2 years post treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03606421
Study type Observational
Source University Health Network, Toronto
Contact David Shultz, MD
Phone 416-946-4501
Email david.shultz@rmp.uhn.ca
Status Recruiting
Phase
Start date October 1, 2018
Completion date June 30, 2026
View Details
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