Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly

Status Completed

Clinical Trial Summary

This study aims to investigate the effect of inhaled anesthetics with a low fresh gas flow on cognitive function of elderly patients undergoing elective surgery

Clinical Trial Description

Geriatric patients scheduled to undergo surgery were tested with Mini Mental State Examination (MMSE) in the preoperative visit. MMSE was repeated postoperatively at the 6th hour, the 1st, 3rd, and 7th day. Visual analogue scale (VAS) test was performed simultaneously on the postoperative 6th hour, the 1st, 3rd, and 7th day. Two cohorts were created according to the amount of fresh gas flow (low flow vs high flow) in the maintenance phase of the inhalational anesthetic. MMSE scores were compared between cohorts and baseline. VAS scores were compared between cohorts. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05548998
Study type	Observational
Source	Prof. Dr. Cemil Tascioglu Education and Research Hospital Organization
Contact
Status	Completed
Phase
Start date	May 1, 2019
Completion date	November 1, 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05754567` - CONCEPTT Kids International Neurodevelopmental Outcomes Among Offspring of Women With Type 1 Diabetes
Completed	`NCT05080777` - Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems	N/A
Not yet recruiting	`NCT03276377` - VItamin K Inhibition and NeurocoGnition (VIKING)	N/A
Completed	`NCT04175223` - Impact of Probiotics in HIV-positive Patients With Neurocognitive Disorders	N/A
Completed	`NCT03538522` - A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831	Phase 2
Recruiting	`NCT05732285` - A Pilot Randomized Controlled Trial: CoINTEGRATE	N/A
Recruiting	`NCT04095962` - Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia	N/A
Not yet recruiting	`NCT04113577` - COgilus Remediation in Alzheimer Patients (CORA)
Recruiting	`NCT06320639` - DRIVing Simulator and People With NeuroCognitive Disorders
Recruiting	`NCT06105320` - COGNIFOOD-Changing the Carbohydrate/Fat-ratio to Prevent Cognitive Decline and Alzheimer Pathology: A Pilot Study	N/A
Completed	`NCT03050385` - Cognitive Rehabilitation During Transcranial Direct Current Stimulation	N/A
Active, not recruiting	`NCT06372002` - Effectiveness and Cost-Effectiveness of Cognitive Stimulation Therapy - Spain (CST-ES) in People Living With Dementia	N/A
Recruiting	`NCT05508789` - A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)	Phase 3
Recruiting	`NCT03926351` - High Dose Omega 3 in People at Risk for Dementia	Phase 2
Recruiting	`NCT05504681` - Integration of Neurocognitive Biomarkers Into a Neuro-Oncology Clinic
Completed	`NCT04168268` - Patient-reported Outcome Measures After Post-anesthesia Care Unit Delirium
Recruiting	`NCT04825847` - Neurocognitive Disorders After Major Surgery in Elderly	N/A
Active, not recruiting	`NCT02958670` - Imaging Tau Deposition in the Brain of Elderly Subjects	N/A
Enrolling by invitation	`NCT02652598` - Evaluate the Effects of Tolcapone on Cognitive and Behavioral Dysfunction in Patients With BI and NCD	Phase 2
Completed	`NCT02825732` - MEMORA-Caregiver : Risk Factors of Caregiver Burden Among Patients With Neurocognitive Disorders or Subjective Cognitive Complaint	N/A