Concordance Between Mini-Mental Stats Examination (MMSE) and an Adapted Version of the MMSE in Reunion Island Population (MMS-Run)

Neurocognitive Deficit Clinical Trial

— MMS-R-ep  

Official title:

Concordance Between Mini-Mental Stats Examination (MMSE) and an Adapted Version of the MMSE in Reunion Island Population (MMS-Run) : Preliminary Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05858489
• Other study ID #: 2022/CHU/30
• Status: Recruiting
• Start date: April 14, 2023
• Est. completion date: June 2024

Study information

• Verified date: July 2023
• Source: Centre Hospitalier Universitaire de la Réunion
• Contact: Bénédicte CASALONGA, MD
• Phone: +262 (0) 262 90 56 80
• Email: benedicte.casalonga[@]chu-reunion.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Illeteracy concerns more than 38% of Réunion Island's people older than 65 years old, which makes it an important risk factor for dementia and a limit to neurocognitive test's administration.

The MMSRun is a Mini Mental State Examination's version adapted to illeteracy and Réunionese culture, inspired by Hindi Mental State Examination's work. It allows a way better participation during neurocognitive evaluation, but it has never been validated.

This study is a peliminary study to a validation, where the concordance between scores obtained from MMSRun and from the consensual version of Mini Mental State Examination proposed by GRECO (Groupe de Réflexion sur les Evaluations Cognitives) - the only french version validated - on a hospitalized and eldery population will be analyzed.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: June 2024
• Est. primary completion date: April 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Patient who needs a cognitive evaluation by MMSe/MMS-RUN during usual medical care

• Patient born and living in Réunion Island

• Patient hospitalized in geriatrics department or in the departement of physical medecine and rehabilitation

• Patient who agrees to participate in the study and who does not oppose to the use of his data

Exclusion Criteria:

• Patient with hearing and visual disorder that can interfere in cognitive test administration

• Patient with altered state of consciousness (Glasgow score different of 15)

• Patient diagnosed or having symtoms compatible with a psychiatric pathology with psychosis (altered perception of reality)

• Patient with a current and severe addiction to Alcohol or any other drug (smoking excluded)

• Patient deprived of liberty by judicial or administrative decision and patient under curatorship or guardianship

Related Conditions & MeSH terms

• Cognition Disorders
• Neurocognitive Deficit

Intervention

Other:
• Mini-Mental State Examination (MMSE)
Each patient will be evaluated by MMSE then by the adapted version of MMSE

Locations

Country	Name	City	State
Réunion	CHU de La Réunion	Saint-Denis

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de la Réunion

Country where clinical trial is conducted

Réunion, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Total scoring of MMSE	30 questions, good response to a question = 1, bad response to a question = 0, global scoring between 0 and 30,; Pathological threshold according to the socio-cultural level : without diploma : total score <22; secondary education without the 3rd class : total score <23; secondary education from 3rd class to the senior year class (without bachelor degree); higher education : total score <26	Day 0
Primary	Total scoring of MMS-RUN	30 questions, good response to a question = 1, bad response to a question = 0, total score between 0 and 30,; Pathological threshold according to the socio-cultural level : without diploma : total score <22; secondary education without the 3rd class : total score <23; secondary education from 3rd class to the senior year class (without bachelor degree); higher education : total score <26	Day 1