Trial of Tolcapone With Oxaliplatin for Neuroblastoma

Status Terminated

Clinical Trial Summary

The purpose of this research study is to evaluate an investigational drug (Tolcapone) alone and in combination with oxaliplatin, for relapsed and refractory neuroblastoma. Tolcapone is approved by the U.S. Food and Drug Administration (FDA) for adults, but is an investigational drug in this study because it has not been approved in pediatrics for this indication. Oxaliplatin, although a drug approved by the FDA for other cancers, is investigational for treatment of neuroblastoma in this study. This study will look at the safety and tolerability of tolcapone in combination with oxaliplatin as well as the tumors response to this study drug.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Neuroblastoma

Clinical Trial Details

NCT number	NCT02630043
Study type	Interventional
Source	Milton S. Hershey Medical Center
Contact
Status	Terminated
Phase	Phase 1
Start date	December 2015
Completion date	July 2019

View Details

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