Neuroblastoma Clinical Trial
Official title:
Analysis of Intersectin Expression in Primary Human Neuroblastomas
RATIONALE: Studying protein expression in samples of tumor tissue from patients with cancer
in the laboratory may help doctors learn more about changes that occur in DNA and identify
biomarkers related to cancer. It may also help doctors find better ways to treat
neuroblastoma.
PURPOSE: This laboratory studying is looking at protein expression in tumor tissue samples
from patients with neuroblastoma.
OBJECTIVES:
- To determine whether intersectin (ITSN1) proteins are present at elevated levels in
primary human tumor samples.
OUTLINE: Archived tumor tissue samples are analyzed for intersectin (ITSN1) expression by
western blot assays with enhanced chemiluminescence and exposed to X-ray film. The films are
scanned, and levels of ITSN1 signal are quantified by densitometry.
;
Observational Model: Case-Only, Time Perspective: Retrospective
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