The Effect of Epidural Steroid Use in Patients With Continous Epidural Block in PHN Patients.

Neuralgia,Postherpetic Clinical Trial

Official title:

The Effect of Epidural Steroid Use on Pain Relief in Patients With Continuous Epidural Nerve Block in Postherpetic Neuralgia Patients.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03995563
• Other study ID #: 2019-04-011
• Status: Recruiting
• Phase: Phase 4
• Start date: May 15, 2019
• Est. completion date: November 30, 2020

Study information

• Verified date: June 2019
• Source: Korea University Guro Hospital
• Contact: Jung Eun Kim, MD, PhD
• Phone: +82-10-7271-5391
• Email: geri200[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The efficiency of epidural steroid injection in patients who has postherpetic neuralgia is well known. In this study, the purpose is whether the continous epidural steroid injection is effective or not.

Description:

Continous epidural injection will be done during 10 days. D group will be injected a 0.19% ropivacaine 8mL and dexametasone 1mg every other day during 10 days.

Continous epidural injection will be done during 10 days N group will be injected a 0.19% ropivacaine 8mL only every other day during 10 days

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: November 30, 2020
• Est. primary completion date: May 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Patients who has herpes zoster

• Patients has a period (at least 1month) after onset of herpes zoster

• Patients has a definite symptom along dermatome

• ASA class I - II

• Age : 18 - 80 years

Exclusion Criteria:

• Patients who has a cancer

• Patients who has a neurologic, psychologic, renal, hepatic and hematologic disease

• Patients who has a other dermatologic disease

• Patients who has major operation & procedure history

• Patients who has a other pain origin

• Patients who can not be inserted epidural catheter

Related Conditions & MeSH terms

• Neuralgia
• Neuralgia, Postherpetic
• Neuralgia,Postherpetic

Intervention

Drug:
• Dexamethasone
Continous epidural injection will be done during 10 days. D group will be injected a 0.19% ropivacaine 8mL and dexametasone 1mg every other day during 10 days. .
• Ropivacaine
Continous epidural injection will be done during 10 days Both group will be injected a 0.19% ropivacaine 8mL every other day during 10 days

Locations

Country	Name	City	State
Korea, Republic of	Kangnam sacred heart hospital	Seoul	Yeongdeungpo-gu

Sponsors (1)

Lead Sponsor	Collaborator
Korea University Guro Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	VAS score	The investigator set the primary outcome If there is a 50% reduction of VAS score.	up to 10 days