Could Bisphenol-A Have a Role in the Etiology of Neural Tube Defects

Status Completed

Clinical Trial Summary

Our aim in this study is in patients with a diagnosis of neural tube defect; is the measurement of BPA levels in maternal blood and amniotic fluid.

Clinical Trial Description

This prospective observational study was conducted with 92 patients aged 18 - 45 years who had amniocentesis at 15 - 22 weeks of gestation at Bursa Yüksek İhtisas Training and Research Hospital between April 15, 2021 and April 15, 2022. Patients were divided into two groups according to amniocentesis indications. Group 1: patients with abnormal maternal serum screening test or prenatal diagnosis test, patients with abnormal ultrasonography findings (45 patients), Group 2: patients with pre-diagnosis of NTD (47 patients). During the amniocentesis procedure, the first 5cc amniotic fluid and maternal serum samples were collected from the patients. The obtained samples were stored at -80°C until the end of the study. After all samples were collected, BPA values were measured by ELISA method. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05454085
Study type	Interventional
Source	Sanliurfa Mehmet Akif Inan Education and Research Hospital
Contact
Status	Completed
Phase	N/A
Start date	April 15, 2021
Completion date	April 15, 2022

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