Optic Nerve Diseases Clinical Trial
Official title:
Effect of Trabeculectomy on Peripapillary Retinal Nerve Fiber Layer Thickness Using Spectral Domain Optical Coherence Tomography
At present, trabeculectomy is the most common performed and effective surgical method of
filtration surgery for patients with medically uncontrolled glaucoma.
The aim of this prospective observational case study is to determine changes of the
peripapillary retinal nerve fiber layer thickness using spectral domain optical coherence
tomography in patients with glaucoma after surgical reduction of intraocular pressure.
Baseline and postoperative measurement of the peripapillary retinal nerve fiber layer (RNFL)
thickness will be performed using the following spectral domain optical coherence tomography
(OCT): Cirrus™ HD-OCT (Carl Zeiss Meditec) and Spectralis® Heidelberg-Engineering.
The main outcome measures will be changes in overall and quadrant RNFL thickness with
respect to reduction in intraocular pressure (IOP), correlation between RNFL thickness and
alteration in visual field and predictive factors of postoperative IOP-reduction and changes
of RNFL thickness.
;
Observational Model: Cohort, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05130385 -
High Resolution Optical Coherence Tomography
|
||
Terminated |
NCT00359632 -
Study to Evaluate Eye Function in Patients Taking Linezolid for Six Weeks or Greater
|
Phase 3 | |
Completed |
NCT01270126 -
Trial of Alternating Current Stimulation in Optic Neuropathy
|
N/A | |
Not yet recruiting |
NCT04289909 -
Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)
|
N/A | |
Active, not recruiting |
NCT02376881 -
Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study)
|
Phase 3 | |
Completed |
NCT04125043 -
Accuracy of the Red Reflex Test in the Pediatric Population
|
||
Completed |
NCT02582164 -
Long-Working Distance OCT for Children
|
N/A | |
Recruiting |
NCT06139523 -
Optimize Pediatric OCT Imaging
|
||
Completed |
NCT01404247 -
Spectral Domain Optical Coherence Tomography Imaging of the Eyes of Neonates
|
Phase 1 | |
Recruiting |
NCT05626426 -
Electrical Stimulation for the Treatment of Optic Neuropathies
|
N/A | |
Completed |
NCT04891211 -
Retinal Changes in Vitamin D Deficiency
|
N/A | |
Completed |
NCT01280877 -
Paraorbital-Occipital Alternating Current Stimulation Therapy for Optic Neuropathy (MCT_optnerve)
|
N/A | |
Recruiting |
NCT04634383 -
A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With Blindness
|
N/A |