Clinical Trials Logo
  1. Home
  2. Nerve Block
  3. NCT06133725

TAPB Combined With RSB Versus ESPB for Postoperative Analgesia After Laparoscopic Liver Resection

Nerve Block Clinical Trial

Official title:
Transversus Abdominis Plane Block Combined With Rectus Sheath Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Laparoscopic Liver Resection

Clinical Trial Summary

Postoperative pain after laparoscopic hepatectomy is composed of multiple factors, and the peak pain of postoperative pain mainly occurs within the first 24 hours, so it is particularly important to find an appropriate analgesic method. Transversus abdominis plane block (TAPB) and Rectus sheath blocks (RSB) are widely used in abdominal surgery, but too deep a needle tip during RSB may puncture abdominal organs. TAPB and RSB can only provide somatic analgesia, but lack visceral analgesia. Recently, Erector spinae plane block (ESPB) has been used in some studies for analgesia after abdominal surgery. The purpose of this study is to compare the analgesic effect and postoperative recovery effect of erector spinae plane block and transverse abdominis plane block combined with rectus sheath block in patients undergoing laparoscopic hepatectomy. Therefore, this study has important clinical implications.

Clinical Trial Description

In a double-blind randomized controlled study, researchers randomized 60 patients undergoing laparoscopic hepatectomy to TAPB combined with RSB or ESPB, with both groups receiving additional standardized treatment, including multimodal analgesia. The main outcome was the consumption of morphine within 24 hours after surgery. Secondary outcomes included the number of rescue analgesia at 1h, 2h, 4h, 8h and 24 hours after surgery, VAS scores in resting and coughing at 1h, 2h, 4h, 8h and 24h after surgery, CVP values at 5, 10, 15 and 30min after nerve block, QoR-15 patient questionnaire scores before and 24h after surgery, and postoperative liver function (the percentage increase of AST and ALT compare with preoperative), postoperative complications and discharge time. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06133725
Study type Interventional
Source Tongji Hospital
Contact Yi Zhang, Dr.
Phone 13986039131
Email doc_zhang18@163.com
Status Not yet recruiting
Phase N/A
Start date November 15, 2023
Completion date December 1, 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT04633850 - Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients
Completed NCT03652103 - Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy Phase 4
Completed NCT03631914 - Intelligent Needle Tip Tracking Using Ultrasound Imaging for Infraclavicular Brachial Plexus Blocks N/A
Completed NCT03244631 - Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection N/A
Completed NCT05034601 - ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure N/A
Completed NCT03740815 - Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection N/A
Not yet recruiting NCT03978780 - Erector Spinae Block vs. Placebo Block Study N/A
Not yet recruiting NCT04101019 - Sphenopalatine Ganglion Block to Treat Shoulder Pain After Laparoscopic Surgery N/A
Recruiting NCT02903719 - The Effect of Phrenic Nerve Block on Postoperative Shoulder Pain in Patients for Liver Resection. Phase 4
Completed NCT03211949 - Ultrasound Guided Topographic Mapping of Medial Antebrachial Cutaneous Nerve N/A
Completed NCT05549011 - PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
Suspended NCT03291691 - Protective Nerve Stimulation in Regional Anesthesia
Completed NCT03771742 - Modified Paramedic Sagittal vs. Transverse TMQLB N/A
Recruiting NCT04480320 - Sonography-guided Pericapsular Never Group Block for Hip Arthroplasty N/A
Active, not recruiting NCT05555147 - The Effect of Bilateral Infraorbital and Infratrochlear Nerve Block on Perioperative Period of Hypophysectomy N/A
Not yet recruiting NCT04298580 - Timing Effect of Ultrasound-Guided PVB After Robotic Cardiac Surgery N/A
Completed NCT03658421 - Dexmedetomidine as Adjuvant for FNB in TKA N/A
Completed NCT03667898 - Intelligent Needle Tip Tracking Using Ultrasound Imaging for Lumbar Plexus Blocks N/A
Terminated NCT03316118 - US Guided GNB vs Saline Injection for TKA Phase 4
Completed NCT03317600 - Postamputation Pain: Peripheral Mechanisms N/A