Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery

Nerve Block Clinical Trial

Official title:

Investigation of Analgesic Effect of Long Thoracic Nerve Blockade After VATS (Video-Assisted Thoracoscopic Surgery) Operation

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03483415
• Other study ID #: 2011-KAEK-25 2018/02-01
• Status: Not yet recruiting
• Phase: N/A
• First received: March 19, 2018
• Last updated: March 23, 2018
• Start date: May 1, 2018
• Est. completion date: April 1, 2019

Study information

• Verified date: March 2018
• Source: Bursa Yüksek Ihtisas Education and Research Hospital
• Contact: korgün Ökmen, M.D
• Phone: +902242955000
• Email: korgunokmen[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Video-assisted thoracoscopic surgery (VATS) provides an opportunity to penetrate the thoracic cavity by video through an incision into the chest wall and facilitate surgical operation of lung pathologies.Various regional methods of anesthesia are currently being used to achieve this goal.

The aim of the study was to assess the effectiveness of Long thoracic nerve bloc on postoperative VATS analgesia.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 60
• Est. completion date: April 1, 2019
• Est. primary completion date: April 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class and underwent video-assisted thoracoscopic surgery (VATS).

Exclusion Criteria:

• Previous history of opioid use preoperatively,

• Allergy to local anesthetics,

• The presence of any systemic infection,

• Uncontrolled arterial hypertension,

• Uncontrolled diabetes mellitus.

Related Conditions & MeSH terms

• Nerve Block
• Video-Assisted Thoracic Surgery

Intervention

Drug:
• Morphine Sulfate
Intravenous morphine infusion with PCA: Solution was concentration of 0.5 mg/mL. Loading dose of 1 mg, 0.5 mg of bolus dose and 20 min of locking time.
• Bupivacaine
Ultrasound guided Long thoracic nerve blockage with 5 ml % 0.25 bupivacaine

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Bursa Yüksek Ihtisas Education and Research Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	morphine consumption	morphine consumption	Postoperative 24 hours
Secondary	Visual Analog Scale	Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0=no pain, 10=intolerable pain)	Postoperative 24 hours
Secondary	side effect (Hypotension)	side effect Hypotension	Postoperative 24 hours
Secondary	additional analgesic use	additional analgesic use	Postoperative 24 hours
Secondary	side effect (Nausea and vomiting)	Nausea and vomiting scale; 1. Nausea and vomiting scale (nausea-vomiting scale (NVS): 1. No nausea is present, 2. Mild nausea is present. 3. Severe nausea is present. 4. Vomiting is present) In case of a NVS score of >3, an anti-emetic drug was administered.	Postoperative 24 hours
Secondary	side effect (Ramsay Sedation Scale (RSS)	Ramsay Sedation Scale (Ramsay Sedation Scale (RSS) : 1. Anxiety, agitation are present; 2. Cooperated, awake; 3. Sedatized, response to commands; 4. Sleepy, immediately awoken by auditory stimulus or glabella tap; 5. Sleepy, deep response to auditory stimulus or glabella tap and 6. Sleepy, no response to auditory stimulus or glabella tap)	Postoperative 24 hours