Post-operative Analgesia Efficacy Using Ultrasound-guided Transmuscular Quadratus Lumborum Block Versus Ultrasound-guided Quadratus Lumborum Type II Block.

Nerve Block Clinical Trial

Official title:

Post-operative Analgesia Efficacy Using Ultrasound-guided Transmuscular Quadratus Lumborum Block Versus Ultrasound-guided Quadratus Lumborum Type II Block.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03100994
• Other study ID #: 1-105-05-157
• Status: Recruiting
• Phase: Phase 4
• First received: March 24, 2017
• Last updated: March 29, 2017
• Start date: March 28, 2017
• Est. completion date: July 2018

Study information

• Verified date: March 2017
• Source: Tri-Service General Hospital
• Contact: Hsuan-Cheng Wu, Dr.
• Email: aibrain[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Post-operative analgesia efficacy using ultrasound-guided transmuscular quadratus lumborum block versus ultrasound-guided quadratus lumborum type II block

Description:

The Quadratus Lumborum (QL) Block is an ultrasound-guided technique described by Rafael Blanco in 2007. The nerves to the lower abdominal wall can be anesthetized by injecting local anesthetics between the quadratus lumborum muscle and latissimus dorsi muscle, which is called quadratus lumborum type II block. 〝 Transmuscular quadratus lumborum block demonstrates that injectate spreads over the posterior abdominal wall to the psoas major muscle and includes the upper branches of the lumbar plexus.〞described by Adhikary in 2016. However there are no published reports comparing the 2 techniques. In our study, compared of ultrasound-guided QL2-blocks with transmuscular quadratus lumborum block to investigate analgesic consumption, pain level, opioid related side effects and mobilization.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 180
• Est. completion date: July 2018
• Est. primary completion date: July 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• American Society of Anesthesiologists classification (ASA) 1~3

• adequate communication skills

• Body mass index < 32

Exclusion Criteria:

chronic pain neurological illness/ neuropathy contraindication against local anesthetics

Related Conditions & MeSH terms

• Nerve Block

Intervention

Drug:
• Bupivacaine
injecting anesthetics to different local

Device:
• Ultrasound
Ultrasound guided nerve block

Locations

Country	Name	City	State
Taiwan	Tri-Service General Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Tri-Service General Hospital

Country where clinical trial is conducted

Taiwan, 

References & Publications (2)

Adhikary SD, El-Boghdadly K, Nasralah Z, Sarwani N, Nixon AM, Chin KJ. A radiologic and anatomic assessment of injectate spread following transmuscular quadratus lumborum block in cadavers. Anaesthesia. 2017 Jan;72(1):73-79. doi: 10.1111/anae.13647. — View Citation

Blanco R, Ansari T, Riad W, Shetty N. Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Pain After Cesarean Delivery: A Randomized Controlled Trial. Reg Anesth Pain Med. 2016 Nov/Dec;41(6):757-762. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	morphine consumption	morphine consumption	48 hours
Secondary	Severity of postoperative pain via visual analogue pain scale (VAS)	Total cumulative morphine dose in mg used in the first 48 hours after surgery	48 hours
Secondary	Nausea or vomiting	Severity of nausea or vomiting in the first 48 hours after surgery. Severe :3 Moderate:2 Mild:1 None: 0	48 hours
Secondary	time to mobilization	Time to mobile in the first 48 hours after surgery	48 hours
Secondary	Skin itch	Severity of skin itch in the first 48 hours after surgery. Severe :3 Moderate:2 Mild:1 None: 0	48 hours