Clinical Trials Logo

Clinical Trial Summary

A single arm, open-label pilot study is designed to determine the safety and effectiveness of anti-CD19 CAR NK cell injection (KN5501) in patients with immune nephropathy. 36 patients are planned to be enrolled in the dose-escalation trial. The primary endpoints are DLT and TEAEs. The secondary endpoints are the overall response rates (ORR) and disease control rate (DCR)


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06469190
Study type Interventional
Source Changhai Hospital
Contact Bian Qi, Dr
Phone 86-13817797610
Email angelbq@126.com
Status Not yet recruiting
Phase Early Phase 1
Start date June 20, 2024
Completion date June 20, 2026

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT05530356 - Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study
Recruiting NCT01448889 - Normobaric Hyperoxygenation for Prevention of Contrast Induced Nephropathy N/A
Active, not recruiting NCT05026021 - Prediction of BKvirus Nephropathy Risk by the NEPHROVIR Method in Kidney Transplant Patients With BKvirus Viremia
Completed NCT02470247 - Interest of Remote Ischemic Preconditioning for Prevention of Contrast Medium-induced Nephropathy in High Risk Patients N/A
Recruiting NCT05511779 - Study to Confirm of the Safety and Tolerability of Brincidofovir in Subjects With BK Virus Infection (Viremia) After Kidney Transplantation Phase 2
Active, not recruiting NCT03584217 - Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study Phase 1/Phase 2
Active, not recruiting NCT03620773 - Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes Phase 1/Phase 2
Completed NCT03618420 - Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function Phase 1/Phase 2
Completed NCT02575092 - The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment Phase 2/Phase 3
Recruiting NCT05839314 - Effect of Huaier Granule on the Treatment of Idiopathic Membranous Nephropathy Phase 4
Completed NCT01638663 - Effect of the Aquaretic Tolvaptan on Nitric Oxide System (TORA) Phase 2
Completed NCT01208701 - The Effects of Atorvastatin on the Nitrogen Oxide-system in Patients With Type 2 Diabetes and Nephropathy Phase 2
Completed NCT01214746 - The Effects of Atorvastatin on the Nitric Oxide-system in Healthy Young Man Phase 2
Completed NCT01213498 - The Effects of Atorvastatin on the Nitric Oxide-system in Patients With Non-diabetic Nephropathy Phase 2
Active, not recruiting NCT00655330 - Probucol Combined With Valsartan in Reducing Proteinuria in Diabetes Nephropathy N/A
Completed NCT00308347 - A Research Study to Evaluate the Renal (Kidney) Protective Effects of Losartan in Patients With Non-insulin Dependent Diabetes (0954-147)(COMPLETED) Phase 3
Terminated NCT00579995 - A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate N/A
Completed NCT05986474 - Development of Synthetic Medical Data Generation Technology to Predict Postoperative Complications
Recruiting NCT03886714 - Screening for Fabry Disease in Renal Transplantation
Recruiting NCT06325059 - The Role of Renal Progenitors and Polyploid Tubular Cell Response in Glomerular and Tubular Diseases N/A