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Nephritis, Hereditary clinical trials

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NCT ID: NCT04937907 Recruiting - Clinical trials for Alport Syndrome, X-Linked

Study of Hydroxychloroquine in Patients With X-linked Alport Syndrome in China (CHXLAS)

CHXLAS
Start date: September 8, 2021
Phase: Phase 2
Study type: Interventional

This Phase 2 randomized controlled trial will study the safety, tolerability, and efficacy of Hydroxychloroquine in qualified patients with Alport syndrome. The trial will be open-label, randomized, controlled and will enroll up to 50 patients.

NCT ID: NCT02378805 Recruiting - Alport Syndrome Clinical Trials

European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Start date: July 1995
Phase:
Study type: Observational [Patient Registry]

The hereditary type IV collagen disease Alport syndrome inevitably leads to end-stage renal disease. Currently there are no therapies known to improve outcome. Our non-interventional, observational study investigates, if medications such as ACE-inhibitors can (1) delay time to dialysis and (2) improve life-expectancy within three generations of Alport-families in Europe.

NCT ID: NCT00481130 Recruiting - Alport Syndrome Clinical Trials

Alport Syndrome Treatments and Outcomes Registry

ASTOR
Start date: September 2007
Phase:
Study type: Observational [Patient Registry]

ASTOR's primary purpose is to enroll families and patients with a history of Alport syndrome in a central registry. The information we gather will be used as a basis for studies designed to test potential treatments for Alport syndrome. ASTOR also aims to provide patients, families and physicians with the most up-to-date information about Alport syndrome.