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The Effect of Conbercept Injection Through Different Routes for Neovascular Glaucoma

Neovascular Glaucoma Clinical Trial

Official title:
The Effect of Conbercept Injection Through Different Routes for Neovascular Glaucoma

Clinical Trial Summary

The neovascular glaucoma (NVG) is a refractory type of secondary glaucoma and often lead to frustrated treatment and blindness. It has been confirmed high levels of vascular endothelial growth factor (VEGF) in NVG. Conbercept is an anti-VEGF agent，its role in regression of other neovascular disorders such as wet-type age-related macular degeneration and diabetic retinopathy has been described. Investigators aim to evaluate the efficacy and safety of intracameral and intravitreal injection of conbercept for the treatment of NVG.

Clinical Trial Description

The neovascular glaucoma (NVG) is a refractory type of secondary glaucoma and often lead to frustrated treatment and blindness. It has been confirmed high levels of vascular endothelial growth factor (VEGF) in NVG. Conbercept is an anti-VEGF agent，Its role in regression of other neovascular disorders such as wet-type age-related macular degeneration and diabetic retinopathy has been described. The intravitreal injection of anti-VEGF agent has shown its therapeutic potential for the early stage of NVG, but not for the late stage. Intracameral injection maybe used as an alternative way for administration. Investigators aim to evaluate the efficacy and safety of intracameral and intravitreal injection of conbercept for the treatment of NVG. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03154892
Study type Interventional
Source Second Affiliated Hospital of Xi'an Jiaotong University
Contact
Status Completed
Phase N/A
Start date April 1, 2017
Completion date December 31, 2017
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