Neoplasms, Intracranial Clinical Trial
Official title:
Comparison the Effectiveness of Postoperative Incentive Spirometry and Noninvasive Mechanical Ventilation in Patients Following Craniotomy
This study will compare the effectiveness of postoperative incentive spirometry and noninvasive mechanical ventilation on pulmonary functions after craniotomy in 60 patients. Patients were randomized into a control group (G-K, n:20), an IS group (G-IS, n:20) and a CPAP (continuous positive airway pressure) group (G-CPAP, n:20)
This study will compare the effectiveness of postoperative incentive spirometry and
noninvasive mechanical ventilation on pulmonary functions after craniotomy in 60 patients.
Patients were randomized into a control group (G-K, n:20), an IS group (G-IS, n:20) and a
CPAP (continuous positive airway pressure) group (G-CPAP, n:20).
The investigators included male or female, between 18 and 60 years old, American Society of
Anesthesiologists score 1, 2 patients in this study. The investigator excluded patients with
significant cardiopulmonary disease like myocardial infarction, obstructive or restrictive
pulmonary disease, liver or kidney failure, chest wall deformities, postoperative lack of
cooperation from this study. In postoperatively, control group will take 4lt/min oxygen with
Plasti-med oxygen therapy mask for 6 hours, IS group will carry out Plasti-med TRIFLO 5 min
per hour for 6 hours, CPAP group will carry out 10 cmH2O noninvasive continuous positive
airway pressure with BIPAP VISION 5 min per hour for 6 hours. Lung functions and arterial
blood gas analysis will be recorded preoperative baseline, postoperative 1st, 6th and 24th
hours.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator)
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT01445691 -
More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
|
Phase 2 |