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Clinical Trial Summary

Necrotizing enterocolitis(NEC) is one of the most serious disease in the newborn infants, and two and more grades of NEC usually lead to surgery, even death. But, it is difficult to predict when to operate the surgery.


Clinical Trial Description

Necrotizing enterocolitis(NEC) is characterized by vomit, abdominal distention, hypoactive bowel sounds and bloody stools, even shock, disseminated intravascular coagulation(DIC) and sepsis. X-ray is shown Intestinal wall gas and/or portal vein pneumatosis and pneumoperitoneum. Two and more grades of NEC in newborn infant is a urgent condition, and whether or not operation is difficult to predict. Here, the investigators develop a score system including five parameters(abdominal circumference, base excess, heart rate, severities of respiratory distress, sepsis) in one retrospective cohort, and the score system is used and assessed to predict the need for surgery in another prospective cohort. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04795453
Study type Observational
Source Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Contact Chen Long, MD, PhD
Phone +8613883559467
Email neuroclong@126.com
Status Recruiting
Phase
Start date March 1, 2021
Completion date December 31, 2024

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