Neonatal Sepsis Clinical Trial
— AKUOfficial title:
Naushero Feroze Neonatal Survival Project: A Cluster Randomized Trial to Determine the Effectiveness of Package of Community Based Interventions to Reduce Neonatal Deaths Due to Birth Asphyxia, Low Birth Weight & Neonatal Sepsis
Verified date | January 2018 |
Source | Aga Khan University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The present study will be carried out in close collaboration with the National Program for
Lady Health Workers, a Ministry of Health program with 100,000 Lady Health Workers covering
60% of the rural population of Pakistan. A team of Lady Health Workers and a Traditional
Birth Attendant will provide care to the mothers and newborns at household level. A Basic
Health Unit will take care of non complicated referrals and provide injectable antibiotics
for neonatal sepsis. Complicated (definitions given in methods section) cases will be
referred by the LHWs/BHUs to the District Headquarter Hospital which will have a functioning
neonatal care unit. The District Health Services, Naushero Feroz, Provincial Department of
Health, Sindh and the Federal Ministry of Health are study collaborators, therefore,
guaranteeing scaling up of interventions at national level.
Hypothesis:
In comparison to a basic package of existing training program of LHWs, enhanced training of
LHWs and TBAs in the early recognition and management of birth asphyxia, serious newborn
infections and LBW (combined with prompt referral) will result in an additional 30% reduction
in neonatal mortality.
Status | Completed |
Enrollment | 37201 |
Est. completion date | January 2013 |
Est. primary completion date | January 2013 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A to 28 Days |
Eligibility |
Inclusion Criteria: Children of ages 1 day to 28 days, within the catchment area of the preformed research. Exclusion Criteria: Those who are not willing to participate in the study. |
Country | Name | City | State |
---|---|---|---|
Pakistan | Pediatric Resaerch Office | Naushahro Firoz | Sindh |
Lead Sponsor | Collaborator |
---|---|
Aga Khan University | Pakistan Ministry of Health, Save the Children |
Pakistan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | neonatal mortality rate Perinatal mortality rates Neonatal mortality rates | the subjects from the two arms would be inquired on information pertaining to socioeconomic position, health services, behaviors and morbibity/ mortality. in view of the most reported concern in the previous studies is noenatal mortality, that information will be primarily important for this research. | two year | |
Secondary | Cause specific mortality rates (due to birth asphyxia,neonatal sepsis and low birth weight) | two years |
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