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NEMO1:NEonatal Seizure Using Medication Off-patent — NEMO1  

Neonatal Seizures Clinical Trial

Official title:
NEMO1: An Open Label Exploratory Dose Finding and Pharmacokinetic Clinical Trial of Bumetanide for the Treatment of Neonatal Seizure Using Medication Off-patent

Clinical Trial Summary

NEMO is a multicentre pan European clinical trial with the aim to develop new treatment strategies for the treatment of neonatal seizures using the loop diuretic bumetanide. There is evidence that bumetanide improves GABAergic function of the current standard drug, phenobarbitone. Bumetanide has been used as a diuretic in term and preterm babies for around thirty years. This trial should confirm that Bumetanide in addition to standard treatment will result in better seizures control.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01434225
Study type Interventional
Source Great Ormond Street Hospital for Children NHS Foundation Trust
Contact
Status Completed
Phase Phase 1/Phase 2
Start date August 2011
Completion date June 2013
View Details
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