Neonatal Disease Clinical Trial
Official title:
Analysis of Differential Proteins and Maternal Influencing Factors of Septic Shock in Neonates Born to ≤32-week Preterm Infants or Infected Mothers During Pregnancy
1. Explore 32 weeks of premature infants or maternal pregnancy infection of newborn septic shock maternal influence factors. 2. Through maternal blood samples before delivery and labor cord blood sample screening and septic shock related proteomics analysis, explore the relationship between the difference protein and septic shock and prognosis, and explore the pathway mechanism, in order to prevent and reduce the occurrence of septic shock in premature infants
| Status | Recruiting |
| Enrollment | 116 |
| Est. completion date | December 31, 2025 |
| Est. primary completion date | September 1, 2025 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 1 Day to 1 Day |
| Eligibility | Inclusion Criteria: - All =32-week premature infants admitted to our NICU; All newborns delivered by the mother infected during pregnancy Exclusion Criteria: - Not delivered in our hospital; congenital cardiovascular development malformation, fetal malformation, genetic metabolic diseases, etc |
| Country | Name | City | State |
|---|---|---|---|
| China | Guangdong Women and Children Hospital | Guangzhou | Guangdong |
| Lead Sponsor | Collaborator |
|---|---|
| Guangdong Women and Children Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | The incidence and mortality of shock | 1/10/2025 |
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