Development of a Novel Methodology Using BMVC Staining as an Assistance to Cancer Cytological Diagnosis

Neck Mass Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01301690
• Other study ID #: FEMH No.:98041-3
• Status: Recruiting
• Phase: N/A
• First received: February 21, 2011
• Last updated: September 16, 2011
• Start date: January 2010

Study information

• Verified date: September 2011
• Source: Far Eastern Memorial Hospital
• Contact: Li-Jen Liao, MD
• Phone: +886-0-8967-1592
• Email: deniro[@]mail2000.com.tw
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

3,6-bis(1-methyl-4-vinylpyridinium) carbazole diiodide (BMVC) is an inorganic chemical compound (Figure1). The uptake of BMVC in cancer cells and normal cells are different. Recently, a simple handheld device (Figure1) based on the fluorescence analysis of stained cells was established to instantly differentiate cancer cells from normal cells. The investigators want to quantitatively measure the fluorescence expression of BMVC in normal and cancer cells and explore the usefulness of this staining in head and neck lumps.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• patients (age range from 18 to 90 years old) with neck lumps, receiving sonographic examination and FNA cytologic study.

Exclusion Criteria:

• No cytology data

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Neck Mass

Locations

Country	Name	City	State
Taiwan	Department of Otolaryngology Far Eastern Memorial Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

References & Publications (1)

Liao LJ, Kang CC, Jan IS, Chen HC, Wang CL, Lou PJ, Chang TC. Improved diagnostic accuracy of malignant neck lumps by a simple BMVC staining assay. Analyst. 2009 Apr;134(4):708-11. doi: 10.1039/b814417f. Epub 2009 Jan 24. — View Citation