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Neck Cancer clinical trials

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NCT ID: NCT06432998 Recruiting - Cancer Pain Clinical Trials

Perineal Massage in Women With Gynecological Cancer

Start date: May 31, 2024
Phase: N/A
Study type: Interventional

The high incidence of gynecological cancers, together with dyspareunia and vaginal stenosis, some of its most frequent sequelae, create the need to continue studying and researching oncological physiotherapy techniques that treat and prevent these sequelae, in order to preserve and/or improve the quality of life of cancer patients. Therefore, through this study, we sought to verify the effectiveness of oncological perineal massage to treat pain during sexual intercourse and vaginal stenosis. The objective of this study will be to demonstrate the effectiveness of a treatment that will consist of a health education session related to the pelvic floor and the consequences related to cancer along with ten sessions of oncological perineal massage that will be carried out for fifty minutes, once a week.

NCT ID: NCT06010381 Completed - Surgery Clinical Trials

Muscle Energy Technique Versus Maitland Mobilization on Shoulder Pain and Disability

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study was to investigate the effect of muscle energy technique versus Maitland's mobilization on shoulder pain and disability after neck dissection surgeries.

NCT ID: NCT05946577 Not yet recruiting - Neck Cancer Clinical Trials

Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter Study

AURACCO
Start date: July 2023
Phase:
Study type: Observational

The aim of the AURACCO study is to evaluate the association between the onset of tinnitus and hearing loss in patients with locally advanced head and neck cancer treated by concomitant chemoradiotherapy or exclusive radiotherapy

NCT ID: NCT05746780 Completed - Larynx Cancer Clinical Trials

Bilateral Elective Neck Dissection in Salvage Total Laryngectomy

Start date: September 1, 2020
Phase:
Study type: Observational

The aim of this study is to evaluate the role of elective bilateral neck dissection in patients with clinically negative lymph nodes (cN0) who underwent salvage total laryngectomy, by estimating the prevalence of histologically positive occult lymph nodes (pN+). Secondary objective will be the assessment of complication rate and the evaluation of 5-year Overall Survival (OS) and 5-year Disease-Specific Survival (DSS) in these patients.

NCT ID: NCT05551767 Recruiting - Neck Cancer Clinical Trials

Induction Immunochemotherapy in Stage III-IVa Head and Neck Cancer

Start date: August 30, 2022
Phase: Phase 2
Study type: Interventional

patients with locally advanced cancer of oropharynx, hypopharynx or larynx and CPS>1 will recieve 3 cycles of induction immunochemotherapy with platinum, 5-FU and pembrolizumab followed by (chemo)radiation.

NCT ID: NCT05549414 Recruiting - Brain Cancer Clinical Trials

Pivotal Study of Proton Radiotherapy Treatments Using Fixed Beam Chair-Based Delivery System

PPTS
Start date: March 30, 2023
Phase: N/A
Study type: Interventional

This study with Chair-Based, Gantry-less Proton System (CBGS) (aka P-CURE Proton Beam Therapy System or Fixed Beam Chair-based Delivery System) is composed of 3 arms, as following: ARM1: Patients with locally recurrent, previously irradiated thoracic cancer indicated for re- irradiation. ARM2: Patients with recurrent Head and Neck, Brain and Spinal Cord tumors, indicated for re- irradiation. ARM3: Patients with unresectable pancreatic cancer. The primary objectives of the study for all arms are: 1. to describe the efficacy (local control after 3 month) and acute toxicity for patients treated with a fully-integrated CBGS and (2) to compare treatment plans between the fully-integrated CBGS and Photon therapy defined for each patient, based upon OAR sparing for comparable target coverage.

NCT ID: NCT05472506 Withdrawn - Clinical trials for Head and Neck Cancer

Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer

Start date: March 2023
Phase: Phase 1
Study type: Interventional

This is a phase 1b study in adult patients diagnosed with resistant or recurrent head and neck squamous cell carcinoma (HNSCC) designed to assess the safety and tolerability of IK-175 in combination with nivolumab. Disease response, pharmacokinetics (PK), pharmacodynamics, and response biomarkers will also be assessed.

NCT ID: NCT05246891 Completed - Rehabilitation Clinical Trials

Rehabilitation Nursing Program in Otolaryngology

Start date: July 1, 2018
Phase:
Study type: Observational

The European Commission's current political guidelines demonstrate into a joint plan aimed at improving and controlling cancer disease. Head and neck cancer (HNC) are the sixth most common cancer worldwide. The surgery is one of the most effective treatments, however it significantly compromises the self-care and functional capacity of the patients, so the intervention the Rehabilitation Nurse (RN) is essential. Objective: Compare the degree of dependence in discharge from patients undergoing HNC surgery with RN intervention versus general nursing care (not RN intervention). The specific objective is to analyze the role of confounders in the effect of the RN intervention on the patient dependence. Seventy-nine patients with RN intervention who undergoing a different type of surgery (1-Neck dissection, 2-Total laryngectomy with neck dissection, 3-Pelviglossomandibulectomy with neck dissection and tracheotomy, 4-Pelviglossomandibulectomy with neck dissection, pectorals major flap and tracheotomy) and all patients who undergoing the same type of surgery without RN intervention (n=72).

NCT ID: NCT04905030 Enrolling by invitation - Cervical Cancer Clinical Trials

Education, Immigration and HPV Vaccination: an Informational Randomized Trial

Start date: April 28, 2021
Phase: N/A
Study type: Interventional

Counteracting misinformation on childhood vaccines remains a priority for public health in industrialized countries. Previous research showed that misinformation-induced vaccine hesitancy particularly concerns very highly or very lowly educated parents, and, especially in Europe, specific groups of immigrants. Misinformation framing directly targets specific sub-population of parents by exploiting different cognitive biases, and specific concerns based on cultural norms: this project aims at testing the effectiveness of similar framing techniques applied to positive information on the HPV vaccine by conducting a Randomized Controlled Trial in Stockholm, Sweden. It randomizes emotionally and scientifically/statistically framed information addressing the specific concerns reported by previous literature.

NCT ID: NCT04750434 Recruiting - Neck Cancer Clinical Trials

PET MRI as a Staging Tool for Head and Neck Cancer

Start date: March 3, 2020
Phase:
Study type: Observational

To explore the use of PET/MRI in the staging and pretreatment evaluation of patients with head and neck cancer and to compare this modality to standard PET/CT imaging.