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Nearsightedness clinical trials

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NCT ID: NCT06229119 Not yet recruiting - Nearsightedness Clinical Trials

Vault Evaluation After ICL Implantation

Start date: January 29, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the lens vault after implantation of an implantable collamer lens (ICL). The ICL is designed to be implanted in front of the eye, without removing the natural lens. Because of this, it is also known as a phakic IOL. The ICL has already been approved by the U.S. Food and Drug Administration (FDA) to treat mid to high degrees of refractive errors such nearsightedness (also called myopia) with or without astigmatism. Once the artificial lens is implanted, a space between the ICL and the crystalline lens is created, which is called vault.

NCT ID: NCT03918915 Active, not recruiting - Nearsightedness Clinical Trials

The Safety and Efficacy of SYD-101 in Children With Myopia

STAR
Start date: April 24, 2019
Phase: Phase 3
Study type: Interventional

Myopia, or nearsightedness, is the most common eye disorder, often affecting more than 40% of adults in Europe, Asia and the USA. Severe myopia is associated with an increased risk of developing other eye conditions such as glucoma, cataracts and retinal detachment, which may lead to blindness. Early treatment of myopia in children could help slow the condition and minimize the risk of complications later in life. This study investigates the use of SYD-101, an eye solution, in slowing-down the progression of myopia in children.

NCT ID: NCT03479827 Completed - Nearsightedness Clinical Trials

Measuring the Peripheral Optical Quality of The Eye

Start date: August 31, 2018
Phase:
Study type: Observational

The goal of the study is to quantify wavefront aberration profiles of the eye with and without contact lens across the visual field. This will enable us to investigate the impact of the aberration on retinal image quality.

NCT ID: NCT02576483 Recruiting - Astigmatism Clinical Trials

An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

Start date: July 2015
Phase:
Study type: Observational

The principle investigator is evaluating self-reported quality of vision and quality of life in physicians undergoing LASIK, SMILE and PRK surgery.

NCT ID: NCT02565537 Active, not recruiting - Astigmatism Clinical Trials

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

Start date: October 2015
Phase: N/A
Study type: Interventional

The investigators are comparing outcomes of LASIK surgery using a high definition wavefront-guided laser to a wavefront-optimized laser in patients with nearsightedness with and without astigmatism.

NCT ID: NCT01013493 Completed - Myopia Clinical Trials

Association Between Breastfeeding and Likelihood of Myopia in 6-7 Years Old Children

Start date: September 2008
Phase: N/A
Study type: Observational

Myopia is the main reason of vision loss in the world which is seen in 30.4 million adults in USA (1). In a myopic eye, images are focused in front of retina because, cornea and crystalline lens become more powerful in focusing the image or the eye axis become too long (axial myopia) (2). Myopia prevalence in adolescents has been raised in recent years and nowadays it has reached to 10-25% and 60-80% in western and eastern countries respectively (3). Tehran eye study showed that the prevalence of myopia in Tehran is 21.8% and 17.2% based on manifest and cycloplegic refraction respectively (4). One study in Dezful, Iran showed that 3.7% of 7-15 years old children are myopic (5). Today potential role of early life nutrition in myopia development in later life is becoming an attractive field of study. It has been shown that until weaning; breast milk is the main source of many nutrients [such as docosahexaenoic acid (DHA)] which are important for photoreceptors and cortical neuronal development (6). But results about the relationship between breastfeeding and likelihood of childhood myopia are controversial. A hypothesis-generating study (7) showed an independent and inverse relationship between breastfeeding and likelihood of myopia in 10-12 year old Singaporean children. However, data pulled from three English birth cohorts done in 10-11y and 15-16y children did not show any effect (8). To examine the association between breastfeeding pattern and likelihood of myopia in 6-7y children, a retrospective case-control study is designed in National Nutrition and Food Technology research Institute of Iran. This study will try to assess breastfeeding pattern and almost all cofactors which may relate to myopia.

NCT ID: NCT00778570 Recruiting - Astigmatism Clinical Trials

Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)

Start date: February 2007
Phase: N/A
Study type: Observational

The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation (ASA) over a wide range of refractive errors The working hypothesis is that there will be no difference in clinical outcomes between patients treated with LASIK or ASA.