Upper Extremity and Muscle Oxygenation

Near-infrared Spectroscopy Clinical Trial

Official title:

Investigation of the Correlation Between Upper Extremity Fatigue Level and Muscle Oxygenation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06294223
• Other study ID #: SaglikBilU
• Status: Recruiting
• Phase: N/A
• Start date: March 1, 2024
• Est. completion date: March 1, 2025

Study information

• Verified date: March 2024
• Source: Saglik Bilimleri Universitesi
• Contact: Esra Pehlivan, Ass. Prof
• Phone: 05058527913
• Email: esra.pehlivan[@]sbu.edu.tr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study was to measure the acute change in oxygen saturation of skeletal muscle during resistance exercise in the upper extremity using near-infrared spectroscopy.

Description:

Our study aims to determine the acute oxygen response in the upper extremity muscles against a resistance exercise fatigue protocol, in order to demonstrate the effect of muscle oxygenation levels on the occurrence of symptoms such as fatigue in upper extremity use, and to provide reference information for the development of exercise programs.

It is known that resistance exercise increases resting energy expenditure and promotes fat oxidation for weight loss. Changes in cardiopulmonary function that occur in chronic diseases reduce oxygen uptake and decrease energy production, leading to increased fatigue. Resistance exercises in chronic diseases can regulate an individual's energy production capacity.

The main objective of our study is to investigate the effect of muscle oxygenation levels on the occurrence of symptoms such as fatigue by determining the oxygen response in the upper extremity muscles based on a resistance exercise protocol.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: March 1, 2025
• Est. primary completion date: March 1, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Volunteering to participate in the study

• Being over 18 years old

• Having a Body Mass Index (BMI) value between 23-30 kg/m2

• Absence of comorbid disease of the orthopedic, neurological, cardiopulmonery system

Exclusion Criteria:

• Smoking / alcohol use

• Presence of orthopedic disease effecting the upper extremity or previous surgery

• Presence of cardiopulmonery disease that prevents exercise

• Participants who performed resistance exercise regulary for more than 6 months

Related Conditions & MeSH terms

• Muscle Oxygenation
• Near-infrared Spectroscopy

Intervention

Device:
• Exercise follow up with near-infrared spectroscopy
Exercises will be followed by near-infrared spectroscopy. Fatigue protocol will be applied.

Locations

Country	Name	City	State
Turkey	Saglik Bilimleri University	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Saglik Bilimleri Universitesi

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Determination of Blood Pressure	Systolic/diastolic blood pressure will be determined with a digital blood pressure monitor and will be recorded in mmHg. Measurements will be taken via the right brachial artery in a comfortable position.	Measurement will be made before and immediately after exercise.
Primary	Saturation Measurement	Oxygen saturation will be measured with a pulse oximeter device and recorded on the form.	Measurement will be made before and immediately after exercise.
Primary	Muscle Oxygenation Measurement	MOXY Pro (Moxy 3, Firmware 1.1 Hutchinson MN, USA), a near-infrared spectroscopy device, will be used to measure the muscle oxygen rate (SmO2) and total hemoglobin amount (tHb) of the biceps brachii muscle.	Baseline.
Primary	Determination of Heart Rate	Heart rate will be determined with a digital blood pressure monitor and will be recorded in BPM.	Measurement will be made before and immediately after exercise.