Circulation and Oxygenation Changes of Deep Tissue Respond on LLLT

Near Infrared Spectroscopy Clinical Trial

Official title:

Circulation and Oxygenation Changes of Deep Tissue Respond on Low Level Light/Laser Therapy (LLLT) in the Healthy Population

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04936165
• Other study ID #: Deep Optical Theranastics
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 25, 2021
• Est. completion date: December 31, 2021

Study information

• Verified date: February 2021
• Source: Chinese Academy of Medical Sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study aims to investigate the circulation and oxygenation changes of deep tissue respond on low level light/laser therapy (LLLT) in the healthy population. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to noninvasively monitor hemodynamic indicators of brain and forearm muscle groups, including total hemoglobin ([tHb]), and blood flow (BF) and oxygen consumption (VO2).

Description:

Low level light/laser therapy (LLLT) employs visible or near-infrared light generated from a laser or light emitting diode (LED) system. It has beneficial effects on a wide range of disease, including improving wound healing, reducing pain, improving memory, treat cancer, and many other human applications. This study aims to investigate the circulation and oxygenation changes of deep tissue respond on low level light/laser therapy (LLLT) in the healthy population. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to noninvasively monitor hemodynamic indicators of brain and forearm muscle groups, including total hemoglobin ([tHb]), and blood flow (BF) and oxygen consumption (VO2). Then the investigators concluded the effect of LLLT, according to compare the difference between the experimental group and control group.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• Healthy participants with no strenuous exercise or alcohol consumption prior to the test

Exclusion Criteria:

• having risk factors associated with cardiovascular disease

Related Conditions & MeSH terms

• Near Infrared Spectroscopy

Intervention

Procedure:
• Low-Level Laser Therapy
Use 810-nm-photosource to irradiate the participants' brain and forearm for 10 minutes with a water-cooling radiator to keep it at 25 ± 0.5 ?.

Locations

Country	Name	City	State
China	NIRS assessment for brain death	Tianjin	Tianjin

Sponsors (1)

Lead Sponsor	Collaborator
Ting Li

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	?[HbO2]	changes of oxyhemoglobin concentration	through study completion, an average of 1 year
Primary	?[Hb]	changes of deoxy-hemoglobin concentration	through study completion, an average of 1 year
Primary	?[tHb]	changes of total hemoglobin concentration	through study completion, an average of 1 year
Secondary	Subcutaneous fat thickness	the subcutaneous fat thickness of the forearm	through study completion, an average of 1 year