Nausea Clinical Trial
Official title:
Patient Recovery After Orthopedic Surgery Under Nerve Blocks With Sedation in Foot and Ankle Patients (FA) and Nerve Block With Either Sedation or General Anesthesia (GA) in Total Shoulder Arthroplasty (TSA) Patients. A Pilot Study
Nausea after surgery may negatively influence patient satisfaction, may delay discharge, and cause unexpected hospital admissions. The trend toward ambulatory surgery has increased the focus on postoperative nausea, but published evidence is not based on standardized criteria for assessment. Therefore, the results for postoperative nausea are very diverse, especially reports on nausea incidence after regional anesthesia, i.e. spinal anesthesia. When peripheral nerve blocks have been applied for postoperative pain control, they significantly reduce postoperative pain, opioid consumption and side effects; patients receiving general anesthesia (GA) and nerve blocks are thought likely to have less nausea than patients receiving GA alone. This study is a pilot study looking at the incidence and intensity of nausea after orthopedic surgery under nerve blocks in foot and ankle (FA) patients and under nerve blocks with either sedation or GA in total shoulder arthroplasty (TSA) patients. The results of this study will help power a future randomized controlled trial, comparing the incidence and intensity of nausea in FA patients receiving GA through laryngeal mask airway (LMA) versus spinal anesthesia.
Nausea after surgery may negatively influence patient satisfaction, may delay discharge, and
cause unexpected hospital admissions. The trend toward ambulatory surgery has increased the
focus on postoperative nausea, but published evidence is not based on standardized criteria
for assessment. Therefore, the results for postoperative nausea are very diverse, especially
reports on nausea incidence after regional anesthesia, i.e. spinal anesthesia. This is due to
varying data sources, such as nurse notes and/or patient reports, and a lack of a consistent
antiemetic and pain medication protocol. The results of this study will help power a future
randomized controlled trial, comparing the incidence and intensity of nausea in FA patients
receiving GA through laryngeal mask airway (LMA) versus spinal anesthesia.
When peripheral nerve blocks have been applied for postoperative pain control, they
significantly reduce postoperative pain, opioid consumption and side effects; patients
receiving GA and nerve blocks are thought likely to have less nausea than patients receiving
GA alone, due a reduction in pain leading to reduction in need for emetogenic opioids.
This study is a pilot study looking at the incidence and intensity of nausea after orthopedic
surgery under nerve blocks in foot and ankle (FA) patients and under nerve blocks with either
sedation or GA in total shoulder arthroplasty (TSA) patients. At the author's institution,
TSA is commonly performed with a brachial plexus block and either GA or intravenous sedation.
TSA patients represent a model system for the effect of GA on nausea among patients receiving
nerve blocks.
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