Nausea Clinical Trial
Official title:
Relationship Between Elevated Serum Serotonin Levels in Symptomatic Patients With Hyperemezis
Serotonin excretion was investigated in the nausea and vomiting associated with hiperemezis gravid arum.
The occurrence of severe nausea and vomiting of early pregnancy (hiperemezis gravid arum) is
estimated between 0.3% to 1% of all pregnancies. Although hiperemezis gravid arum has been
recognized for a long time, its pathophysiologic mechanisms are still poorly understood.
Many theories have been advocated, but to date none of these have been convincing.
It has been demonstrated that the nausea and vomiting associated with increased in serotonin
liberation. This has provided a rationale for the treatment of these symptoms with specific
serotonin antagonists.
The aim of this trial was to investigate the possible relationship between hiperemezis
gravid arum and serotonin liberation.
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Observational Model: Case-Only, Time Perspective: Cross-Sectional
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