Nausea Clinical Trial - Efficacy of Aprepitant (Emend®) in Children

Status Completed

Clinical Trial Summary

The purpose of this study is to find out whether or not adding aprepitant(Emend®) to the standard therapy will help children who receive chemotherapy to have less nausea and vomiting.

Clinical Trial Description

1.1 Primary Aim To determine the efficacy of aprepitant (Emend®) in preventing and reducing chemotherapy-induced nausea and vomiting (CINV) when added to standard antiemetic drug regimens for children receiving highly emetogenic chemotherapy. The working hypothesis will be that standard therapy + aprepitant is superior at preventing CINV than standard therapy + placebo. 1.2 Secondary Aim To evaluate the safety and toxicity of aprepitant (Emend®) in children receiving highly emetogenic chemotherapy when compared to standard antiemetic therapy + placebo. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01661335
Study type	Interventional
Source	University of Oklahoma
Contact
Status	Completed
Phase	Phase 3
Start date	June 1, 2012
Completion date	June 29, 2017

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See also
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