Nausea Clinical Trial
Official title:
Postoperative Nausea and Vomiting Are Similar When Propofol or Sevoflurane Are Used as Adjuvant to Remifentanil During Anaesthesia for Gynaecological Surgery
The purpose of this study is to determine whether sevoflurane-remifentanil anaesthesia is similar to propofol-remifentanil anaesthesia concerning post- operative nausea and vomiting.
Propofol and sevoflurane anaesthesia are used world wide at the anaesthetists discretion.
Propofol is superior to inhalational anaesthetics as anaesthesia for patients at risk of
post operative nausea and vomiting (PONV) as PONV is diminished. However, when remifentanil
is used as adjuvant to sevoflurane, the total dose of the latter is reduced.
Therefore, we wanted to investigate if sevoflurane-remifentanil anaesthesia is similar to
propofol-remifentanil anaesthesia with emphasis on nausea, vomiting and total PONV during 24
hours.
In the post anaesthesia care unit (PACU) and in the surgical ward nausea was scored on a
visual analogue score. Vomiting was registered.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
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