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Nasopharyngeal Cancer clinical trials

View clinical trials related to Nasopharyngeal Cancer.

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NCT ID: NCT00439426 Completed - Clinical trials for Nasopharyngeal Cancer

A Study of Xeloda (Capecitabine) in Combination With XELOX (Oxaliplatin) in Patients With Metastatic Nasopharyngeal Cancer.

Start date: April 2007
Phase: Phase 2
Study type: Interventional

This single arm study will assess the efficacy and safety of Xeloda + oxaliplatin when given as first line treatment for patients with metastatic nasopharyngeal cancer. Patients will receive Xeloda (1000mg/m2 bid orally from day 1 to day 14, followed by a rest period of 7 days) plus oxaliplatin (130mg/m2 iv infusion on day 1 of each 21 day cycle) for 6-8 cycles. The anticipated time on study treatment is until disease progression, and the target sample size is <100 individuals.

NCT ID: NCT00430378 Completed - Xerostomia Clinical Trials

Acupuncture for Prevention of Radiation-Induced Xerostomia

Start date: January 2007
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn if acupuncture is effective in preventing xerostomia (dry mouth) in cancer patients who receive radiation treatment to the head and neck area. Researchers also want to learn whether acupuncture lowers the severity of dry mouth that is experienced by these patients. Primary Objective: -Investigate if acupuncture is effective in preventing xerostomia among cancer patients at Fudan University Cancer Hospital (Cancer Hospital) who receive radiation treatment to the head and neck area. Secondary Objectives: - Determine whether acupuncture reduces the severity of xerostomia. - Determine the feasibility of providing acupuncture treatment to patients at Cancer Hospital who are receiving radiation treatment for cancer of the head and/or neck area.

NCT ID: NCT00370890 Completed - Clinical trials for Nasopharyngeal Cancer

A Trial of Adjuvant Chemotherapy in Nasopharyngeal Carcinoma Patients With Residual Epstein-Barr Virus (EBV) DNA Following Radiotherapy

Start date: September 4, 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to study the benefit of adjuvant chemotherapy using gemcitabine and cisplatin in high risk NPC patients with residual EBV DNA following primary radiotherapy with or without concurrent cisplatin.

NCT ID: NCT00304694 Recruiting - Clinical trials for Nasopharyngeal Cancer

Whole-Body 18F-FDG PET in Induction Chemotherapeutic Response for Advanced NPC Patients

Start date: March 2006
Phase: N/A
Study type: Observational

18F-FDG PET, a whole-body imaging technology based on glucose metabolism, can effectively detect subclinical and clinical therapeutic responses at stages that are earlier than those detected by conventional approaches. We propose to conduct a prospective study to evaluate therapeutic response using 18F-FDG PET before and after induction chemotherapy for locally advanced NPC patients.

NCT ID: NCT00141765 Completed - Wilms Tumor Clinical Trials

Study of High-Dose Chemotherapy With Bone Marrow or Stem Cell Transplant for Rare Poor-Prognosis Cancers

Start date: January 1997
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether very high dosages of chemotherapy will improve the chance of surviving cancer.

NCT ID: NCT00078546 Completed - Clinical trials for Nasopharyngeal Cancer

EBV-Specific CTLs Following CD45 Antibody to Patients With Epstein-Barr Virus (EBV) + Nasopharyngeal Carcinoma (NPC)

CLANC
Start date: September 2003
Phase: Phase 1
Study type: Interventional

To determine the safety of the combination of CD45 monoclonal antibody (Mab) followed by intravenous injection of EBV specific CTL in patients with nasopharyngeal cancer. To compare the expansion, persistence and anti-tumor effects of the EBV specific CTL given after CD45 Mab administration with that observed in our first study. To obtain preliminary information on the safety and response to an extended dosage regimen of EBV-specific CTL in patients, who have stable disease or a partial response after the initial dose of EBV-specific CTL.