Nasolacrimal Duct Obstruction Clinical Trial
— NLD2Official title:
A Prospective Study of Surgical Procedures for the Treatment of Persistent Nasolacrimal Duct Obstruction in Children Less Than Four Years Old
Verified date | May 2012 |
Source | Jaeb Center for Health Research |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Observational |
The purpose of this study is:
- To report the success proportions for the treatment of persistent nasolacrimal duct
obstruction for three surgical procedures: balloon catheter dilation, nasolacrimal
intubation, and simple probing.
- To obtain descriptive data regarding symptoms and quality of life in patients receiving
each type of surgical procedure, and to compare success proportions between patients
undergoing balloon catheter dilation and those undergoing nasolacrimal intubation.
Status | Completed |
Enrollment | 194 |
Est. completion date | February 2008 |
Est. primary completion date | February 2008 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 6 Months to 47 Months |
Eligibility |
Inclusion Criteria: - Age 6 - < 48 months - Parent/guardian has the ability to complete a written questionnaire - Onset of NLDO symptoms and/or signs prior to 6 months chronological age - Presence of epiphora, increased tear film, and/or mucopurulent discharge in the absence of an upper respiratory infection or an ocular surface irritation - Previous single failed simple probing procedure for nasolacrimal duct obstruction - Investigator has determined the patient requires a second procedure for opening of the nasolacrimal duct Exclusion Criteria: - History of nasolacrimal intubation, balloon catheter dilation, more than one simple probing, or dacryocystorhinostomy - Glaucoma present - Corneal surface disease |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Wilmer Eye Institute | Baltimore | Maryland |
United States | Family Eye Clinic | Lancaster | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
Jaeb Center for Health Research | National Eye Institute (NEI) |
United States,
Repka MX, Chandler DL, Holmes JM, Hoover DL, Morse CL, Schloff S, Silbert DI, Tien DR; Pediatric Eye Disease Investigator Group. Balloon catheter dilation and nasolacrimal duct intubation for treatment of nasolacrimal duct obstruction after failed probing — View Citation
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00780741 -
Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old
|
Phase 3 | |
Completed |
NCT00784992 -
A Comparison of Endonasal Dacryocystorhinostomy With and Without Silicone Tubes
|
Phase 4 | |
Recruiting |
NCT06346561 -
The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study
|
N/A | |
Completed |
NCT01233596 -
Monocanalicular Versus Bicanalicular Intubation in the Treatment of Congenital Nasolacrimal Duct Obstruction
|
Phase 3 | |
Recruiting |
NCT06226181 -
Amniotic Membrane for Dacryocystorhinostomy
|
Phase 1 | |
Completed |
NCT00315289 -
Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old
|
Phase 3 | |
Recruiting |
NCT05999630 -
Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer
|
Phase 3 | |
Completed |
NCT01766232 -
Lacrimal Drainage Resistance Study
|
N/A |