Treatment of Early Nasal Polyposis With Topical Triamcinolone

Nasal Polyps Clinical Trial

Official title:

Treatment of Early Nasal Polyposis With Topical Triamcinolone

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01222871
• Other study ID #: 00540
• Status: Terminated
• Phase: Phase 1/Phase 2
• Start date: July 2010
• Est. completion date: August 2012

Study information

• Verified date: June 2018
• Source: Steward St. Elizabeth's Medical Center of Boston, Inc.
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to compare the effectiveness of intranasal Triamcinolone delivered through a bio-absorbable nasal dressing verses oral steroids and a saline soaked dressing, in the treatment and prevention of early nasal polyposis.

Description:

nasopore, a bio-absorbable nasal dressing, may offer an alternative route of sustained steroid drug delivery. The use of topical targeted intranasal steroids may prevent the routine adverse effects of oral steroids while maintaining the same therapeutic / clinical efficacy.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 1
• Est. completion date: August 2012
• Est. primary completion date: July 2012
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age > 18 years

• Patients with early nasal polyposis

Exclusion Criteria:

• Age < 18 years

• Patients with active sinus infections

• Patients on long term steroids

• Allergy or sensitivity to steroids

• Patients with Antrochoanal polyps

• Patients who received topical steroids by bio-resorbable sponge or oral steroids

Related Conditions & MeSH terms

• Nasal Polyps

Intervention

Drug:
• Triamcinolone
Triamcinolone soaked nasopore dressing
• Saline soaked sponge
saline soaked sponge

Locations

Country	Name	City	State
United States	St. Elizabeth's Medical Center, 736 Cambridge St	Brighton	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
Steward St. Elizabeth's Medical Center of Boston, Inc.

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Nasal Endoscopic Exam Findings .	nasal endoscopic exam findings at 2 weeks, 6 weeks and 12 weeks were not collected from any participant.	2 weeks, 6 weeks, 12 weeks were not collected from any participant.